SCHEMBL3340704

SCHEMBL3340704

NC(=O)CC[C@H](N)C(=O)OC(=O)Cc1ccccc1.[NaH]

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.45
MAPK1 P28482 2/20 0.45
ALDH1A1 P00352 1/20 0.45
PAM P19021 1/20 0.44
TSHR P16473 1/20 0.43
ALOX15 P16050 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
KMT2A Q03164 1/20 0.42
LTA4H P09960 3/20 0.39
SLC7A5 Q01650 2/20 0.39
ALPI P09923 1/20 0.39
PKM P14618 1/20 0.39
PTGS1 P23219 1/20 0.39
XIAP P98170 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 1/20 0.38
SLC15A1 P46059 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL402494 0.99 L3MBTL1 (0.46) L3MBTL1MAPK1ALDH1A1PAMTSHR
SCHEMBL28376925 0.84 ALDH1A1 (0.44) L3MBTL1MAPK1ALDH1A1PAMTSHR
SCHEMBL17458666 0.84 ALDH1A1 (0.49) L3MBTL1MAPK1ALDH1A1PAMTSHR
SCHEMBL4810846 0.82 ALPI (0.53) ALOX15BLMPMP22KMT2ALTA4H
SCHEMBL1702340 0.81 ALDH1A1 (0.46) L3MBTL1MAPK1ALDH1A1PAMTSHR
SCHEMBL8740769 0.80 ALDH1A1 (0.51) L3MBTL1MAPK1ALDH1A1PAMTSHR
SCHEMBL15532005 0.80 SLC7A5 (0.58) L3MBTL1MAPK1ALDH1A1PAMTSHR
SCHEMBL28231845 0.80 MMP2 (0.50) L3MBTL1MAPK1ALDH1A1PAMTSHR
SCHEMBL6672089 0.80 LTA4H (0.44) ALDH1A1TSHRALOX15BLMPMP22
SCHEMBL4989088 0.79 LTA4H (0.48) L3MBTL1MAPK1ALDH1A1ALOX15BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS CIBA CORPORATION (US) 2010-06-10 US disclosed
EP-2120846-A2 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS BASF SE (DE) 2009-11-25 EP disclosed
WO-2008107347-A2 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS BASF SE (CH) 2008-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS MAOA, MAOB, ACMSD L3MBTL1 4501/4885MAPK1 3875/4885ALDH1A1 464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.