SCHEMBL3342324

SCHEMBL3342324

C=CCN1CCC(N)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39
MAPT P10636 2/20 0.36
HRH3 Q9Y5N1 2/20 0.36
ADRA2A P08913 2/20 0.36
ADRA2B P18089 2/20 0.36
ADRA2C P18825 2/20 0.36
ADRA1A P35348 2/20 0.36
LMNA P02545 1/20 0.36
DRD2 P14416 1/20 0.36
HTR2A P28223 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36
OPRK1 P41145 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RAD52 P43351 1/20 0.35
SIGMAR1 Q99720 1/20 0.34
SPHK1 Q9NYA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936092 0.86
SCHEMBL10828113 0.86
SCHEMBL4959156 0.83 SIGMAR1 (0.35) MAPTHRH3ADRA2AADRA2BADRA2C
SCHEMBL24243286 0.78 OPRD1 (0.38) MAPTHRH3ADRA2AADRA2BADRA2C
SCHEMBL4502992 0.78 SIGMAR1 (0.35) MAPTHRH3ADRA2AADRA2BADRA2C
SCHEMBL6530435 0.77 NCF1 (0.46) MAPTHRH3ADRA2AADRA2BADRA2C
SCHEMBL3632233 0.76 SIGMAR1 (0.34) MAPTHRH3ADRA2AADRA2BADRA2C
SCHEMBL10641032 0.76 ADRA2A (0.40) MAPTHRH3ADRA2AADRA2BADRA2C
SCHEMBL10828056 0.76 SIGMAR1 (0.34) MAPTHRH3ADRA2AADRA2BADRA2C
SCHEMBL82611 0.76 CARM1 (0.48) HRH3KDM4EALDH1A1SIGMAR1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219538-B Preparation method of tert-butyl peroxybenzoate 宿迁市万和泰化工有限公司 2025-03-18 CN claimed
CN-119219538-A Preparation method of tert-butyl peroxybenzoate 宿迁市万和泰化工有限公司 2024-12-31 CN claimed
EP-3154941-B1 SMALL MOLECULE LFA-1 INHIBITORS ALLOCYTE PHARMACEUTICALS AG (CH) 2021-01-20 EP claimed
US-20190040008-A1 SMALL MOLECULE LFA-1 INHIBITORS ALLOCYTE PHARMACEUTICALS AG (CH) 2019-02-07 US claimed
US-10077238-B2 Small molecule LFA-1 inhibitors ALLOCYTE PHARMACEUTICALS AG (CH) 2018-09-18 US claimed
US-20170121284-A1 SMALL MOLECULE LFA-1 INHIBITORS ALLOCYTE PHARMACEUTICALS AG (CH) 2017-05-04 US claimed
EP-3154941-A1 SMALL MOLECULE LFA-1 INHIBITORS AlloCyte Pharmaceuticals AG (CH) 2017-04-19 EP claimed
WO-2015189265-A1 SMALL MOLECULE LFA-1 INHIBITORS ALLOCYTE PHARMACEUTICALS AG (CH) 2015-12-17 WO claimed
US-20100113411-A1 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2010-05-06 US claimed
EP-1558600-B1 SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT BOEHRINGER INGELHEIM PHARMA (DE) 2008-05-07 EP claimed
US-20060079504-A1 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG (DE) 2006-04-13 US claimed
US-4618599-A WATER SOLUBILITY RHONE-POULENC SANTE (FR) 1986-10-21 US claimed
CN-119219538-B Preparation method of tert-butyl peroxybenzoate 宿迁市万和泰化工有限公司 2025-03-18 CN disclosed
CN-119219538-A Preparation method of tert-butyl peroxybenzoate 宿迁市万和泰化工有限公司 2024-12-31 CN disclosed
EP-3973999-A1 CONJUGATE OR ITS SALT COMPRISING A GASTRIN-RELEASING PEPTIDE RECEPTOR ANTAGONIST AND USES THEREOF Orano Med (FR) 2022-03-30 EP disclosed
EP-3154941-B1 SMALL MOLECULE LFA-1 INHIBITORS ALLOCYTE PHARMACEUTICALS AG (CH) 2021-01-20 EP disclosed
US-5236931-A Treating anxiety, psychosis, cognitive dysfunction, migrane, cluster headache, trigeminal neuralgia emesis and impaired gastric motility A. H. ROBINS COMPANY, INCORPORATED (US) 1993-08-17 US disclosed
US-5084460-A Psychological disorders, anxiolytic agents and cognition activators A. H. ROBINS COMPANY, INCORPORATED (US) 1992-01-28 US disclosed
US-4247694-A PHOTOSTABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1981-01-27 US disclosed
EP-0021806-A1 2,3-Dihydro-imidazo (2,1-b) benzothiazole derivatives and pharmaceutical compositions containing them JANSSEN PHARMACEUTICA N.V. (BE) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10077238-B2 Small molecule LFA-1 inhibitors ICAM1, VCAM1, ITGB1 GNAI3 638/4885GNAO1 1907/4885GNAI1 392/4885
US-20190040008-A1 SMALL MOLECULE LFA-1 INHIBITORS ICAM1, VCAM1, ITGB1 GNAI3 638/4885GNAO1 1907/4885GNAI1 392/4885
US-20170121284-A1 SMALL MOLECULE LFA-1 INHIBITORS ICAM1, VCAM1, ITGB1 GNAI3 638/4885GNAO1 1907/4885GNAI1 392/4885
US-20100113411-A1 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions CALCRL, CALCR, CALCA GNAI3 472/4885GNAO1 290/4885GNAI1 451/4885
US-20060079504-A1 Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions CALCRL, CALCR, CALCA GNAI3 472/4885GNAO1 290/4885GNAI1 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.