SCHEMBL3351706 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	KDM4E	B2RXH2	2/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	MAPK1	P28482	1/20	0.34

▸	HTT	P42858	1/20	0.34

▸	L3MBTL1	Q9Y468	1/20	0.34

▸	GRM5	P41594	4/20	0.33

▸	PDE10A	Q9Y233	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3347585	0.88	GRM5 (0.34)	KDM4EALDH1A1MAPK1HTTL3MBTL1
SCHEMBL3345928	0.85	GRM5 (0.36)	KDM4EALDH1A1MAPK1HTTL3MBTL1
SCHEMBL3347669	0.83	PDE10A (0.35)	GRM5PDE10A
SCHEMBL3347055	0.81	GRM5 (0.51)	KDM4EALDH1A1MAPK1HTTL3MBTL1
SCHEMBL3346856	0.81	GRM5 (0.52)	KDM4EALDH1A1MAPK1HTTL3MBTL1
SCHEMBL3347641	0.80	GRM5 (0.38)	KDM4EALDH1A1MAPK1HTTL3MBTL1
SCHEMBL3345855	0.79	KDM4E (0.33)	KDM4EALDH1A1MAPK1HTTL3MBTL1
SCHEMBL3347285	0.79	KDM4E (0.37)	KDM4EALDH1A1MAPK1HTTL3MBTL1
SCHEMBL3345594	0.78	GRM5 (0.40)	KDM4EALDH1A1MAPK1HTTL3MBTL1
SCHEMBL3347306	0.78	CHRNB2 (0.44)	GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2010063487-A1	PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE	MERZ PHARMA GMBH & CO. KGAA (DE)	2010-06-10	—	—	WO	disclosed