Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354706 | 0.88 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3355827 | 0.86 | HTR7 (0.42) | L3MBTL1ALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3353063 | 0.85 | HTR7 (0.42) | L3MBTL1ALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3358021 | 0.83 | HTR7 (0.47) | ALDH1A1MEN1PKMKMT2AHTR7 | |
| SCHEMBL3352191 | 0.83 | SCD (0.47) | SCDHTR7HTR1AHTR1DHTR1B | |
| SCHEMBL3354104 | 0.81 | DRD2 (0.60) | ALDH1A1CYP2D6SCDMEN1PKM | |
| SCHEMBL13537407 | 0.81 | SCD (0.45) | SCDHTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3353280 | 0.80 | HTR7 (0.53) | PKMHTR7HTR1AHTR1DHTR1B | |
| SCHEMBL3354826 | 0.79 | HTR7 (0.48) | ALDH1A1CYP2D6MEN1KMT2AHTR7 | |
| SCHEMBL7805698 | 0.78 | HTR7 (0.45) | ALDH1A1CYP2C19DRD4PKMHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |