Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | ABL2 | P42684 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355827 | 0.86 | HTR7 (0.42) | HTR7L3MBTL1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL3354706 | 0.85 | ALDH1A1 (0.44) | HTR7L3MBTL1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL3354101 | 0.85 | L3MBTL1 (0.48) | HTR7L3MBTL1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL3358021 | 0.83 | HTR7 (0.47) | HTR7ALDH1A1DRD2SLC6A4HTR1A | |
| SCHEMBL3354906 | 0.83 | ABL1 (0.44) | HTR7DRD2SLC6A4ABL1EGFR | |
| SCHEMBL3354104 | 0.81 | DRD2 (0.60) | HTR7ALDH1A1CYP2D6DRD2SLC6A4 | |
| SCHEMBL13537340 | 0.81 | DRD2 (0.40) | HTR7DRD2SLC6A4ABL1EGFR | |
| SCHEMBL7805956 | 0.80 | KDM4E (0.52) | L3MBTL1ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL3353280 | 0.80 | HTR7 (0.53) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL3354826 | 0.79 | HTR7 (0.48) | HTR7ALDH1A1CYP2D6DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |