Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 12/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12931454 | 0.92 | DNM1 (0.79) | DNM1HTTAPAF1HSP90AA1RAD52 | |
| SCHEMBL9935871 | 0.91 | DNM1 (0.77) | DNM1HTTHSP90AA1RAD52KMT2A | |
| SCHEMBL7550034 | 0.91 | — | — | |
| SCHEMBL33718 | 0.89 | DNM1 (0.79) | DNM1HTTAPAF1HSP90AA1RAD52 | |
| SCHEMBL7065524 | 0.89 | DNM1 (0.79) | DNM1HTTAPAF1HSP90AA1RAD52 | |
| SCHEMBL13923673 | 0.89 | DNM1 (0.79) | DNM1HTTAPAF1HSP90AA1RAD52 | |
| SCHEMBL12938361 | 0.88 | DNM1 (0.62) | DNM1HTTAPAF1HSP90AA1RAD52 | |
| SCHEMBL231912 | 0.87 | — | — | |
| SCHEMBL1292726 | 0.87 | DNM1 (0.81) | DNM1HTTHSP90AA1RAD52KMT2A | |
| SCHEMBL14781561 | 0.87 | MEN1 (0.60) | DNM1HTTKMT2AMEN1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180177690-A1 | COMPOSITION FOR LIFTING COLOR AND/OR ALTERING THE COLOR OF KERATINOUS SUBSTRATES | L'OREAL (FR) | 2018-06-28 | — | — | US | disclosed |
| US-8946367-B2 | Polymerizable carbamate and thiocarbamate compounds, polymers derived from them, and compositions thereof | ISP INVESTMENTS INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-8915973-B1 | Agent for altering the color of keratin fibers containing a rheology modifying polymer and a fatty substance in an alkaline cream system | L'OREAL (FR) | 2014-12-23 | — | — | US | disclosed |
| US-8802070-B2 | Compositions containing a phospholipid, a nonionic surfactant, and an anionic silicone for lifting color and/or imparting shine onto keratinous substrates | L'OREAL (FR) | 2014-08-12 | — | — | US | disclosed |
| US-8802071-B2 | Compositions containing a fatty quaternary amine, a nonionic surfactant, and a carboxylate compound for lifting color and/or imparting shine onto keratinous substrates | L'OREAL (FR) | 2014-08-12 | — | — | US | disclosed |
| US-8802069-B2 | Compositions containing a phospholipid, a nonionic surfactant, and a carboxylate compound for lifting color and/or imparting shine onto keratinous substrates | L'OREAL (FR) | 2014-08-12 | — | — | US | disclosed |
| US-8795644-B2 | Compositions containing a phospholipid, a nonionic surfactant, and a phosphate ester for lifting color and/or imparting shine onto keratinous substrates | L'OREAL (FR) | 2014-08-05 | — | — | US | disclosed |
| US-8795645-B2 | Compositions containing a fatty quaternary amine, a nonionic surfactant, and an anionic silicone for lifting color and/or imparting shine onto keratinous substrates | L'OREAL (FR) | 2014-08-05 | — | — | US | disclosed |
| US-8758735-B2 | Compositions containing a fatty quaternary amine, a nonionic surfactant, and a phosphate ester for lifting color and/or imparting shine onto keratinous substrates | L'OREAL (FR) | 2014-06-24 | — | — | US | disclosed |
| US-8721742-B2 | Agent for altering the color of keratin fibers comprising a fatty substance, a rheology modifying polymer, and direct dyes in a liquid emulsion system | L'OREAL (FR) | 2014-05-13 | — | — | US | disclosed |
| US-20120325253-A1 | COMPOSITIONS CONTAINING A PHOSPHOLIPID, A NONIONIC SURFACTANT, AND AN ANIONIC SILICONE FOR LIFTING COLOR AND/OR IMPARTING SHINE ONTO KERATINOUS SUBSTRATES | L'OREAL S.A. (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120325252-A1 | COMPOSITIONS CONTAINING A FATTY MONOAMINE, A NONIONIC SURFACTANT, AND AN ANIONIC SILICONE FOR LIFTING COLOR AND/OR IMPARTING SHINE ONTO KERATINOUS SUBSTRATES | L'ORéAL S.A. (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120325244-A1 | EMULSION DYEING COMPOSITION CONTAINING AT LEAST ONE PHOSPHOLIPID, AT LEAST ONE NONIONIC SURFACTANT AND AT LEAST ONE SILICONE, AND METHOD OF USING SAME | L'ORéAL S.A. (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120325258-A1 | COMPOSITIONS CONTAINING A FATTY QUATERNARY AMINE, A NONIONIC SURFACTANT, AND AN ANIONIC SILICONE FOR LIFTING COLOR AND/OR IMPARTING SHINE ONTO KERATINOUS SUBSTRATES | L'OREAL S.A. (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120325240-A1 | EMULSION DYEING COMPOSITION CONTAINING AT LEAST ONE AMINE, AT LEAST ONE NONIONIC SURFACTANT AND AT LEAST ONE CARBOXYLIC ACID, AND METHOD OF USING SAME | L'OREAL S.A. (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120325249-A1 | COMPOSITIONS CONTAINING A POLYAMINE, A NONIONIC SURFACTANT, AND AN ANIONIC SILICONE FOR LIFTING COLOR AND/OR IMPARTING SHINE ONTO KERATINOUS SUBSTRATES | L'OREAL S.A. (FR) | 2012-12-27 | — | — | US | disclosed |
| US-20120325261-A1 | EMULSION DYEING COMPOSITION CONTAINING AT LEAST ONE QUATERNARY AMINE, AT LEAST ONE NONIONIC SURFACTANT AND AT LEAST ONE CARBOXYLIC ACID AND METHOD OF USING THE SAME | L'OREAL S.A. (FR) | 2012-12-27 | — | — | US | disclosed |
| US-8066781-B2 | Composition comprising at least one fatty substance and at least one cationic polymer, dyeing or lightening process using it and devices therefor | L'OREAL S.A. (FR) | 2011-11-29 | — | — | US | disclosed |
| US-20100154136-A1 | COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE CATIONIC POLYMER, DYEING OR LIGHTENING PROCESS USING IT AND DEVICES THEREFOR | L'OREAL S.A. (FR) | 2010-06-24 | — | — | US | disclosed |
| US-20080282481-A1 | Process for Dyeing the Hair Using an Anionic Coloured Polymer | L'OREAL S.A. (FR) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080282481-A1 | Process for Dyeing the Hair Using an Anionic Coloured Polymer | KRT18, DSG1, KRTCAP2 | DNM1 3090/4885HTT 1726/4885APAF1 3395/4885 |
| US-20100154136-A1 | COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE CATIONIC POLYMER, DYEING OR LIGHTENING PROCESS USING IT AND DEVICES THEREFOR | KRT18, NOTUM, FABP4 | DNM1 4293/4885HTT 4212/4885APAF1 2407/4885 |
| US-20180177690-A1 | COMPOSITION FOR LIFTING COLOR AND/OR ALTERING THE COLOR OF KERATINOUS SUBSTRATES | KRT18, DSG1, VCL | DNM1 2532/4885HTT 3690/4885APAF1 3133/4885 |
| US-20120325249-A1 | COMPOSITIONS CONTAINING A POLYAMINE, A NONIONIC SURFACTANT, AND AN ANIONIC SILICONE FOR LIFTING COLOR AND/OR IMPARTING SHINE ONTO KERATINOUS SUBSTRATES | SGMS1, SMOX, SRM | DNM1 2207/4885HTT 4022/4885APAF1 2449/4885 |
| US-20120325253-A1 | COMPOSITIONS CONTAINING A PHOSPHOLIPID, A NONIONIC SURFACTANT, AND AN ANIONIC SILICONE FOR LIFTING COLOR AND/OR IMPARTING SHINE ONTO KERATINOUS SUBSTRATES | ABHD16A, PHOSPHO1, SGMS1 | DNM1 2360/4885HTT 4403/4885APAF1 2813/4885 |
| US-20120325258-A1 | COMPOSITIONS CONTAINING A FATTY QUATERNARY AMINE, A NONIONIC SURFACTANT, AND AN ANIONIC SILICONE FOR LIFTING COLOR AND/OR IMPARTING SHINE ONTO KERATINOUS SUBSTRATES | KRT18, CPT1B, PLOD3 | DNM1 1557/4885HTT 3567/4885APAF1 4158/4885 |
| US-20120325244-A1 | EMULSION DYEING COMPOSITION CONTAINING AT LEAST ONE PHOSPHOLIPID, AT LEAST ONE NONIONIC SURFACTANT AND AT LEAST ONE SILICONE, AND METHOD OF USING SAME | KRT18, PHOSPHO1, SGMS1 | DNM1 1791/4885HTT 3363/4885APAF1 3519/4885 |
| US-20120325240-A1 | EMULSION DYEING COMPOSITION CONTAINING AT LEAST ONE AMINE, AT LEAST ONE NONIONIC SURFACTANT AND AT LEAST ONE CARBOXYLIC ACID, AND METHOD OF USING SAME | KRT18, MAOA, NOTUM | DNM1 1077/4885HTT 2549/4885APAF1 4318/4885 |
| US-20120325261-A1 | EMULSION DYEING COMPOSITION CONTAINING AT LEAST ONE QUATERNARY AMINE, AT LEAST ONE NONIONIC SURFACTANT AND AT LEAST ONE CARBOXYLIC ACID AND METHOD OF USING THE SAME | KRT18, FABP4, PHOSPHO1 | DNM1 513/4885HTT 2583/4885APAF1 4188/4885 |
| US-20120325252-A1 | COMPOSITIONS CONTAINING A FATTY MONOAMINE, A NONIONIC SURFACTANT, AND AN ANIONIC SILICONE FOR LIFTING COLOR AND/OR IMPARTING SHINE ONTO KERATINOUS SUBSTRATES | MAOA, MAOB, CPT1B | DNM1 1950/4885HTT 2636/4885APAF1 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.