Sulfuric Acid

Sulfuric Acid

SCHEMBL3359652

Nc1ccc(N(CCO)CCO)cc1.O.O=S(=O)(O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
TSHR P16473 6/20 0.44
CYP3A4 P08684 4/20 0.44
TDP1 Q9NUW8 4/20 0.44
RECQL P46063 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPK1 P28482 2/20 0.44
PSMD14 O00487 1/20 0.44
GFER P55789 1/20 0.44
NT5E P21589 1/20 0.41
CYP2D6 P10635 1/20 0.38
RAD52 P43351 1/20 0.36
HPGD P15428 2/20 0.35
ALOX15 P16050 2/20 0.35
THRB P10828 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP2C9 P11712 2/20 0.35
MEN1 O00255 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL624610 0.98 ALDH1A1 (0.45) ALDH1A1TSHRCYP3A4TDP1RECQL
4-Aminophenol SCHEMBL15653111 0.91 ALDH1A1 (0.43) ALDH1A1TSHRCYP3A4TDP1RECQL
Water SCHEMBL3359653 0.90 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4TDP1RECQL
Sulfuric Acid SCHEMBL11109463 0.90 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4TDP1RECQL
Sulfuric Acid SCHEMBL9005432 0.90 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4TDP1RECQL
Sulfuric Acid SCHEMBL3892651 0.90 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4TDP1RECQL
SCHEMBL8521178 0.88 ALDH1A1 (0.54) ALDH1A1TSHRCYP3A4TDP1RECQL
SCHEMBL33874 0.88 ALDH1A1 (0.54) ALDH1A1TSHRCYP3A4TDP1RECQL
SCHEMBL28087334 0.88 ALDH1A1 (0.54) ALDH1A1TSHRCYP3A4TDP1RECQL
Sulfuric Acid SCHEMBL1143794 0.88 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4TDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233431-A1 PRETREATMENT COMPOSITION OF A PROCESS FOR DYEING OR BLEACHING KERATIN FIBERS L'OREAL (FR) 2023-07-27 US disclosed
EP-3389622-B1 OXIDIZING COMPOSITION FOR TREATING KERATIN MATERIALS, COMPRISING A FATTY SUBSTANCE AND OXYALKYLENATED SURFACTANTS OREAL (FR) 2023-01-04 EP disclosed
EP-3555069-B1 NOVEL AZOMETHINE DIRECT DYES BEARING AT LEAST ONE CATIONIC CHARGE, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF OREAL (FR) 2022-03-30 EP disclosed
EP-2841168-B1 DYEING PROCESS USING A MIXTURE COMPRISING A BRANCHED C6-C12 POLYOL, OBTAINED FROM AN AEROSOL DEVICE, AND DEVICE THEREFOR OREAL (FR) 2022-02-23 EP disclosed
EP-3544576-B1 DYE COMPOSITION COMPRISING 12-HYDROXYSTEARIC ACID, AN ORGANIC AMINE AND A DYE OREAL (FR) 2021-08-18 EP disclosed
US-10927259-B2 Dissymmetric azomethine direct dyes and process for their preparation, cosmetic composition comprising at least one such dye and use thereof L'OREAL (FR) 2021-02-23 US disclosed
US-10889718-B2 Azomethine direct dyes bearing at least one cationic charge, cosmetic composition comprising at least one such dye, implementation process therefor and use thereof L'OREAL (FR) 2021-01-12 US disclosed
EP-3554466-B1 DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF OREAL (FR) 2020-11-25 EP disclosed
US-20200190329-A1 DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF L'OREAL (FR) 2020-06-18 US disclosed
EP-2515842-B1 DYEING COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND PROPYLENE OXIDE OREAL (FR) 2020-04-29 EP disclosed
WO-2013045627-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST TWO DIOL COMPOUNDS EACH COMPRISING AT LEAST 4 CARBON ATOMS L'OREAL (FR) 2013-04-04 WO disclosed
WO-2013045628-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR OXYETHYLENATED NONIONIC SURFACTANT L'OREAL (FR) 2013-04-04 WO disclosed
WO-2013045626-A1 FOAM DYE COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND PROPYLENE OXIDE L'OREAL (FR) 2013-04-04 WO disclosed
WO-2013045630-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST ONE LIQUID FATTY ALCOHOL AND A PARTICULAR CATIONIC POLYMER L'OREAL (FR) 2013-04-04 WO disclosed
EP-2198853-A1 Composition for the oxidative dyeing of keratinous fibres comprising a fatty material and N,N bis-(beta-hydroxyethyl)-paraphenylenediamine L'OREAL (FR) 2010-06-23 EP disclosed
US-6187268-B1 DEVICE FOR COLORIMETRIC DETECTION OF ANALYTE IN TEST FLUID COMPRISING DRY REAGENT LAYER OVERCOATED WITH TRANSPARENT, FLUID PERMEABLE WATER SWELLABLE MEMBRANE BAYER CORPORATION 2001-02-13 US disclosed
EP-0977034-A2 Transparent flow through membrane for dry reagent analytical devices Bayer Corporation (US) 2000-02-02 EP disclosed
EP-0278621-B1 SUBSTITUTED AMINE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1991-06-12 EP disclosed
US-4295848-A Composition for hair dyeing which contains a para base and an ortho base L'OREAL (FR) 1981-10-20 US disclosed
US-4268264-A ORTHO PRECURSORS SELECTED FROM AROMATIC DIAMINES, AMINOPHENOL, DIPHENOL, AND PHENYLENEDIAMINE L'OREAL (FR) 1981-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927259-B2 Dissymmetric azomethine direct dyes and process for their preparation, cosmetic composition comprising at least one such dye and use thereof KRT18, DSG1, IK ALDH1A1 754/4885TSHR 2280/4885CYP3A4 1251/4885
US-20200190329-A1 DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF KRT18, DSG1, IK ALDH1A1 754/4885TSHR 2280/4885CYP3A4 1251/4885
US-10889718-B2 Azomethine direct dyes bearing at least one cationic charge, cosmetic composition comprising at least one such dye, implementation process therefor and use thereof KRT18, IK, KMO ALDH1A1 1145/4885TSHR 3005/4885CYP3A4 538/4885
US-20230233431-A1 PRETREATMENT COMPOSITION OF A PROCESS FOR DYEING OR BLEACHING KERATIN FIBERS KRT18, COL1A1, CRYAB ALDH1A1 500/4885TSHR 4537/4885CYP3A4 3341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.