SCHEMBL3364797

SCHEMBL3364797

CO/N=C(/C1=NOCCO1)c1ccccc1O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ KMT2A Q03164 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ HRH4 Q9H3N8 1/20 0.32
▸ MGLL Q99685 1/20 0.31
▸ CTNNB1 P35222 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6763775 1.00 LMNA (0.34) LMNATSHRKMT2AMEN1NPC1
SCHEMBL30915236 1.00 LMNA (0.34) LMNATSHRKMT2AMEN1NPC1
SCHEMBL1457093 1.00 LMNA (0.34) LMNATSHRKMT2AMEN1NPC1
SCHEMBL30915237 1.00 LMNA (0.34) LMNATSHRKMT2AMEN1NPC1
SCHEMBL8505944 0.86 DRD4 (0.34) NPC1CTNNB1
SCHEMBL8542898 0.86 DRD4 (0.34) NPC1CTNNB1
SCHEMBL16378821 0.85 KMT2A (0.35) LMNATSHRKMT2AMEN1NPC1
SCHEMBL7683910 0.83 ALDH1A1 (0.32) CTNNB1
SCHEMBL6763805 0.83 MGLL (0.33) TSHRKMT2AMEN1NPC1HRH4
SCHEMBL6763809 0.83 MGLL (0.33) TSHRKMT2AMEN1NPC1HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886774-A Preparation method of fluoxastrobin intermediate 江苏好收成韦恩农化股份有限公司 2024-04-16 — — CN claimed
EP-3303312-B1 PROCESS FOR PREPARING (E)-(5,6-DIHYDRO-1,4,2-DIOXAZINE-3-YL)(2-HYDROXYPHENYL)METHANONE O-METHYL OXIME ARYSTA LIFESCIENCE CORP (JP) 2023-07-19 — — EP claimed
EP-3699178-A1 PROCESS FOR PREPARING FLUOXASTROBIN Arysta LifeScience Corporation (JP) 2020-08-26 — — EP claimed
EP-3019495-B1 PROCESS FOR PREPARING FLUOXASTROBIN ARYSTA LIFESCIENCE CORP (JP) 2020-06-03 — — EP claimed
US-10087152-B2 Process for preparing (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyl oxime ARYSTA LIFESCIENCE CORPORATION (JP) 2018-10-02 — — US claimed
US-20180148423-A1 Process for Preparing (E)-(5,6-Dihydro-1,4,2-Dioxazine-3-YL) (2-Hydroxyphenyl) Methanone O-Methyl Oxime ARYSTA LIFESCIENCE CORPORATION (JP) 2018-05-31 — — US claimed
EP-3303312-A1 PROCESS FOR PREPARING (E)-(5,6-DIHYDRO-1,4,2-DIOXAZINE-3-YL) (2-HYDROXYPHENYL) METHANONE O-METHYL OXIME Arysta LifeScience Corporation (JP) 2018-04-11 — — EP claimed
US-9670171-B2 Process for preparing fluoxastrobin ARYSTA LIFESCIENCE CORP (JP) 2017-06-06 — — US claimed
WO-2016193822-A1 PROCESS FOR PREPARING (E)-(5,6-DIHYDRO-1,4,2-DIOXAZINE-3-YL) (2-HYDROXYPHENYL) METHANONE O-METHYL OXIME ARYSTA LIFESCIENCE CORPORATION (JP) 2016-12-08 — — WO claimed
US-20160237047-A1 PROCESS FOR PREPARING FLUOXASTROBIN ARYSTA LIFESCIENCE CORP (JP) 2016-08-18 — — US claimed
EP-3019495-A1 PROCESS FOR PREPARING FLUOXASTROBIN Arysta LifeScience Corporation (JP) 2016-05-18 — — EP claimed
US-9193698-B2 Process for preparing fluoxastrobin ADVINUS THERAPEUTICS, LTD. (IN) 2015-11-24 — — US claimed
WO-2015006203-A1 PROCESS FOR PREPARING FLUOXASTROBIN ARYSTA LIFESCIENCE CORPORATION (JP) 2015-01-15 — — WO claimed
US-20150011753-A1 PROCESS FOR PREPARING FLUOXASTROBIN ARYSTA LIFESCIENCE CORPORATION (JP) 2015-01-08 — — US claimed
US-12559483-B2 Process for the preparation of fluoxastrobin and intermediates thereof UPL LTD (IN) 2026-02-24 — — US disclosed
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof UPL LTD (IN) 2024-07-02 — — US disclosed
CN-117886774-A Preparation method of fluoxastrobin intermediate 江苏好收成韦恩农化股份有限公司 2024-04-16 — — CN disclosed
US-6005104-A INTERMEDIATES FOR PREPARING COMPOUNDS HAVING FUNGICIDAL PROPERTIES; PREPARED BY REARRANGING O-HYDROXYETHYL-O'-ALKYL-BENZOFURANDIONE DIOXIMES BAYER AKTIENGESELLSCHAFT (DE) 1999-12-21 — — US disclosed
CN-1220665-A Process for preparing 3- (1-hydroxyphenyl-1-alkoxyiminomethyl) dioxazines BAYER AG (DE) 1999-06-23 — — CN disclosed
EP-0712396-B1 SUBSTITUTED AZADIOXACYCLOALKENES AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1998-11-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10087152-B2 Process for preparing (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyl oxime HMOX2, HAO2, HMOX1 LMNA 1510/4885TSHR 3439/4885KMT2A 490/4885
US-20160237047-A1 PROCESS FOR PREPARING FLUOXASTROBIN CYP4X1, MB, HAO2 LMNA 953/4885TSHR 2745/4885KMT2A 2793/4885
US-20180148423-A1 Process for Preparing (E)-(5,6-Dihydro-1,4,2-Dioxazine-3-YL) (2-Hydroxyphenyl) Methanone O-Methyl Oxime HMOX2, HAO2, HMOX1 LMNA 1627/4885TSHR 3409/4885KMT2A 470/4885
US-12024492-B2 Process for preparation of azoxystrobin and intermediates thereof NISCH, STS, SNX2 LMNA 2252/4885TSHR 4550/4885KMT2A 3991/4885
US-12559483-B2 Process for the preparation of fluoxastrobin and intermediates thereof P2RX7, P2RX6, CTRB1 LMNA 1078/4885TSHR 950/4885KMT2A 4777/4885
US-20150011753-A1 PROCESS FOR PREPARING FLUOXASTROBIN CYP4X1, MB, HAO2 LMNA 953/4885TSHR 2745/4885KMT2A 2793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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