SCHEMBL336511

SCHEMBL336511

Cc1ccc(S(=O)(=O)OCC(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGER Q15109 1/20 0.44
GAA P10253 2/20 0.43
STAT3 P40763 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CA1 P00915 3/20 0.41
CA9 Q16790 3/20 0.41
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
CA3 P07451 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
VDR P11473 1/20 0.40
DHODH Q02127 1/20 0.40
TLR9 Q9NR96 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179049 0.89 AGER (0.44) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL116604 0.88 AGER (0.41) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL116676 0.88 AGER (0.41) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL2823373 0.87 AGER (0.43) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL29958689 0.87 AGER (0.43) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL2941601 0.86 AGER (0.42) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL499843 0.85 CA12 (0.42) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL25345480 0.84 AGER (0.41) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL30802773 0.84 AGER (0.41) AGERGAASTAT3ALDH1A1CYP3A4
SCHEMBL20267914 0.84 GAA (0.42) AGERGAASTAT3ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116231075-A Electrolyte containing overcharge-preventing additive and lithium ion battery 湖北亿纬动力有限公司 2023-06-06 CN claimed
CN-105461708-A Quinazoline tyrosine kinase inhibitor, and preparation method and application thereof SHANGHAI SUN-SAIL PHARMACEUTICAL SCIENCE & TECH CO LTD 2016-04-06 CN claimed
US-12612412-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2026-04-28 US disclosed
EP-4620954-A1 CDK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Shandong Luye Pharmaceutical Co., Ltd. (CN) 2025-09-24 EP disclosed
WO-2025087431-A1 PAN-KRAS INHIBITOR AND USE THEREOF IN MEDICINES 贝达药业股份有限公司 2025-05-01 WO disclosed
US-20250136582-A1 SELECT KRAS G12C INHIBITORS AND USES THEREOF 1200 PHARMA LLC (US) 2025-05-01 US disclosed
US-20250105357-A1 ELECTROLYTE SOLVENTS AND METHODS FOR LITHIUM METAL AND LITHIUM ION BATTERIES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-03-27 US disclosed
WO-2025056068-A1 BICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF 上海济煜医药科技有限公司 2025-03-20 WO disclosed
US-12240825-B2 Oxexin 1 receptor antagonists NXERA PHARMA UK LIMITED (GB) 2025-03-04 US disclosed
US-20250034162-A1 IMIDAZOPYRIMIDINES AS EED INHIBITORS AND THE USE THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-01-30 US disclosed
US-12145944-B2 Imidazopyrimidines as EED inhibitors and the use thereof REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-11-19 US disclosed
US-20070099909-A1 N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR CHEN ZHAOGEN 2007-05-03 US disclosed
US-7157488-B2 N-(2-Arylethyl) benzylamines as antagonists of the 5-HT6 receptor ELI LILLY AND COMPANY (US) 2007-01-02 US disclosed
EP-1691777-A2 NOVEL DIFFERENTIAL IMAGING METHOD Medi-Physics, Inc. (US) 2006-08-23 EP disclosed
US-20060009511-A9 N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor CHEN ZHAOGEN 2006-01-12 US disclosed
WO-2005053615-A9 NOVEL DIFFERENTIAL IMAGING METHOD MEDI PHYSICS INC (US) 2005-09-01 WO disclosed
WO-2005053615-A2 NOVEL DIFFERENTIAL IMAGING METHOD MEDI-PHYSICS, INC. (US) 2005-06-16 WO disclosed
EP-1379239-A2 N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR ELI LILLY AND COMPANY (US) 2004-01-14 EP disclosed
WO-2002078693-A2 N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR ELI LILLY AND COMPANY (US) 2002-10-10 WO disclosed
EP-0517041-A1 New Cephem Compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136582-A1 SELECT KRAS G12C INHIBITORS AND USES THEREOF KRAS, NRAS, HRAS AGER 2901/4885GAA 1443/4885STAT3 777/4885
US-12145944-B2 Imidazopyrimidines as EED inhibitors and the use thereof EED, EEF1D, EEF1A1 AGER 4404/4885GAA 3003/4885STAT3 2981/4885
US-20060009511-A9 N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor HTR6, HTR2C, HTR1B AGER 1375/4885GAA 4200/4885STAT3 4642/4885
US-12240825-B2 Oxexin 1 receptor antagonists HCRTR1, HCRTR2, OXTR AGER 1760/4885GAA 3739/4885STAT3 3257/4885
US-20250034162-A1 IMIDAZOPYRIMIDINES AS EED INHIBITORS AND THE USE THEREOF EED, EEF1D, EEF1A1 AGER 4404/4885GAA 3003/4885STAT3 2981/4885
US-12612412-B2 Antiviral heterocyclic compounds ZC3HAV1, NHERF1, HM13 AGER 4201/4885GAA 4300/4885STAT3 2443/4885
US-20250105357-A1 ELECTROLYTE SOLVENTS AND METHODS FOR LITHIUM METAL AND LITHIUM ION BATTERIES LEF1, MLEC, LAGE3 AGER 3262/4885GAA 4050/4885STAT3 110/4885
US-20070099909-A1 N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR HTR6, HTR2C, HTR1B AGER 1375/4885GAA 4200/4885STAT3 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.