Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 14/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.57 |
| ▸ | PDE4A | P27815 | 8/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441489 | 0.82 | PDE4B (0.63) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL31314527 | 0.82 | MEN1 (0.70) | PDE4BMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL2848397 | 0.82 | MEN1 (0.70) | PDE4BMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL3371531 | 0.80 | PDE4D (0.69) | PDE4BPDE4DPDE4APDE4CALDH1A1 | |
| SCHEMBL7913459 | 0.77 | PDE4D (0.70) | PDE4BPDE4DPDE4APDE4CALDH1A1 | |
| SCHEMBL6232036 | 0.77 | MEN1 (0.53) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| SCHEMBL14575985 | 0.76 | PDE4B (0.50) | PDE4BPDE4DPDE4APDE4CMEN1 | |
| SCHEMBL3168608 | 0.76 | SMN1; SMN2 (0.66) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL10568457 | 0.75 | MEN1 (0.64) | MEN1ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL12378894 | 0.75 | MEN1 (0.68) | MEN1ALDH1A1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | KOWA COMPANY, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | SERPINE1, SERPINC1, TFPI | PDE4B 1700/4885PDE4D 1519/4885PDE4A 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.