Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260677 | 0.87 | RAB9A (0.74) | RAB9AGAAKMT2AMEN1NPC1 | |
| SCHEMBL1554424 | 0.81 | TDP1 (0.63) | RAB9AGAAKMT2AMEN1NPC1 | |
| SCHEMBL26364981 | 0.80 | PLK1 (0.52) | RAB9AGAAKMT2AMEN1NPC1 | |
| SCHEMBL15874898 | 0.79 | TDP1 (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4609558 | 0.78 | ALDH1A1 (0.54) | RAB9AGAAKMT2AMEN1NPC1 | |
| SCHEMBL1554602 | 0.77 | TDP1 (0.75) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL12188090 | 0.76 | ALDH1A1 (0.59) | RAB9AGAAKMT2AMEN1NPC1 | |
| SCHEMBL4629167 | 0.76 | ALDH1A1 (0.57) | RAB9AGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8697182 | 0.76 | L3MBTL1 (0.60) | RAB9AGAAKMT2AMEN1NPC1 | |
| SCHEMBL27406580 | 0.76 | LMNA (0.70) | RAB9AGAAKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12480111-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-20250346882-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2025-11-13 | — | — | US | disclosed |
| US-12378541-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250034543-A1 | PENICILLIN-G ACYLASES | CODEXIS INC (US) | 2025-01-30 | — | — | US | disclosed |
| US-20240409916-A1 | PENICILLIN-G ACYLASES | CODEXIS INC (US) | 2024-12-12 | — | — | US | disclosed |
| US-12084697-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2024-09-10 | — | — | US | disclosed |
| CN-110506113-B | Penicillin G acylase | 科德克希思公司 | 2024-05-03 | — | — | CN | disclosed |
| US-11965192-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2024-04-23 | — | — | US | disclosed |
| CN-117737045-A | Penicillin G acylase | 科德克希思公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-111051506-B | Penicillin G acylase | 科德克希思公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20170321202-A1 | PENICILLIN-G ACYLASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-11-09 | — | — | US | disclosed |
| WO-2016179464-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2016-11-10 | — | — | WO | disclosed |
| US-20160326508-A1 | PENICILLIN-G ACYLASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2016-11-10 | — | — | US | disclosed |
| US-8569013-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20120270282-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-8247192-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20100143968-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2010054319-A2 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| EP-0792366-A1 | ENZYME GENE THERAPY CATALYSING PRODRUG EXTRACELLULAR CONVERSION | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996016179-A1 | ENZYME GENE THERAPY CATALYSING PRODRUG EXTRACELLULAR CONVERSION | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270282-A1 | PENICILLIN-G ACYLASES | PGLS, PNP, NAAA | RAB9A 3209/4885GAA 12/4885KMT2A 1693/4885 |
| US-20250034543-A1 | PENICILLIN-G ACYLASES | NAAA, PGLS, PNP | RAB9A 3750/4885GAA 19/4885KMT2A 1396/4885 |
| US-20240409916-A1 | PENICILLIN-G ACYLASES | NAAA, PGLS, PNP | RAB9A 3702/4885GAA 26/4885KMT2A 1545/4885 |
| US-11965192-B2 | Penicillin-G acylases | NAAA, PGLS, PNP | RAB9A 3750/4885GAA 19/4885KMT2A 1396/4885 |
| US-12084697-B2 | Penicillin-G acylases | NAAA, PGLS, PNP | RAB9A 3702/4885GAA 26/4885KMT2A 1545/4885 |
| US-20100143968-A1 | PENICILLIN-G ACYLASES | PGLS, PNP, NAAA | RAB9A 3209/4885GAA 12/4885KMT2A 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.