Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340563 | 0.90 | ALDH1A1 (0.41) | MEN1KMT2ATSHRALDH1A1ACHE | |
| SCHEMBL2608179 | 0.87 | MEN1 (0.39) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL13135081 | 0.83 | THRB (0.36) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL339706 | 0.81 | TSHR (0.38) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL23064187 | 0.81 | THRB (0.38) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL16805859 | 0.81 | THRB (0.47) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL553241 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL23064188 | 0.79 | THRB (0.37) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL194228 | 0.79 | THRB (0.55) | MEN1KMT2ATSHRTHRBALDH1A1 | |
| SCHEMBL13758059 | 0.79 | THRB (0.40) | MEN1KMT2ATSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2012-01-19 | — | — | US | claimed |
| EP-2618845-B1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | CRISTAL DELIVERY B V (NL) | 2020-02-26 | — | — | EP | disclosed |
| US-9339554-B2 | Tunable, biodegradable linker molecules for transient conjugation of components in drug delivery systems, and drug delivery systems prepared therewith | CRISTAL DELIVERY B.V. (NL) | 2016-05-17 | — | — | US | disclosed |
| US-20130261094-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | CRISTAL DELIVERY B.V. (NL) | 2013-10-03 | — | — | US | disclosed |
| EP-2618845-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | Cristal Delivery B.V. (NL) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012039602-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | UNIVERSITEIT UTRECHT HOLDING B.V. (NL) | 2012-03-29 | — | — | WO | disclosed |
| US-8110220-B2 | Temperature sensitive polymers | UNIVERSITEIT UTRECHT (NL) | 2012-02-07 | — | — | US | disclosed |
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | LCT, LDHA, LDHB | MEN1 3434/4885KMT2A 2446/4885TSHR 4451/4885 |
| US-20130261094-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | GSS, PFAS, ABCB1 | MEN1 2768/4885KMT2A 3003/4885TSHR 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.