Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339382 | 0.88 | TSHR (0.31) | TSHR | |
| SCHEMBL339217 | 0.85 | CA1 (0.34) | TSHR | |
| SCHEMBL339839 | 0.82 | TSHR (0.35) | TSHRTHRBMEN1KMT2ATGFBR1 | |
| SCHEMBL10016884 | 0.77 | TSHR (0.32) | TSHRMEN1KMT2A | |
| SCHEMBL3246641 | 0.77 | — | — | |
| SCHEMBL4834711 | 0.75 | TSHR (0.36) | TSHR | |
| SCHEMBL18101450 | 0.73 | THRB (0.39) | TSHRTHRBTGFBR1 | |
| SCHEMBL339706 | 0.73 | TSHR (0.38) | TSHRTHRBMEN1KMT2ATGFBR1 | |
| Lactic Acid SCHEMBL545470 | 0.72 | TGFBR1 (0.40) | MEN1KMT2ATGFBR1 | |
| SCHEMBL799428 | 0.72 | TGFBR1 (0.37) | TSHRTHRBMEN1KMT2ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | LCT, LDHA, LDHB | TSHR 4451/4885THRB 2644/4885MEN1 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.