Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 7/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339382 | 0.92 | TSHR (0.31) | TSHRCTSK | |
| SCHEMBL339899 | 0.85 | TSHR (0.33) | TSHR | |
| SCHEMBL28615632 | 0.81 | CA1 (0.39) | CA1CA2TSHRCTSKACHE | |
| SCHEMBL339839 | 0.77 | TSHR (0.35) | TSHR | |
| SCHEMBL548172 | 0.76 | GPR84 (0.38) | CA1CA2TSHRFAAH | |
| Lactic Acid SCHEMBL545561 | 0.75 | FAAH (0.38) | CA2FAAH | |
| SCHEMBL15821165 | 0.75 | CTSK (0.46) | CA1CA2TSHRCTSKABCB1 | |
| SCHEMBL15942359 | 0.75 | TSHR (0.40) | CA1CA2TSHRCTSKABCB1 | |
| SCHEMBL10016884 | 0.72 | TSHR (0.32) | TSHR | |
| SCHEMBL536884 | 0.72 | ALDH1A1 (0.41) | CA1CA2TSHRABCB1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | LCT, LDHA, LDHB | CA1 439/4885CA2 252/4885TSHR 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.