Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.91 |
| ▸ | GAA | P10253 | 1/20 | 0.91 |
| ▸ | GFER | P55789 | 1/20 | 0.91 |
| ▸ | IDO1 | P14902 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | KDM1A | O60341 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11700730 | 0.95 | MEN1 (0.82) | MEN1KMT2AGAAGFERIDO1 | |
| SCHEMBL9365750 | 0.87 | PKM (0.73) | MEN1KMT2AGAAGFERIDO1 | |
| SCHEMBL12010876 | 0.86 | MEN1 (0.72) | MEN1KMT2AGAAGFERALDH1A1 | |
| SCHEMBL29118884 | 0.85 | PKM (0.73) | MEN1KMT2AGAAGFERALDH1A1 | |
| SCHEMBL5318082 | 0.85 | HPGD (0.74) | MEN1KMT2AGAAGFERALDH1A1 | |
| SCHEMBL97361 | 0.85 | KMT2A (0.68) | MEN1KMT2AGAAGFERALDH1A1 | |
| SCHEMBL14131252 | 0.85 | MEN1 (0.77) | MEN1KMT2AGAAGFERIDO1 | |
| SCHEMBL396617 | 0.84 | MEN1 (0.68) | MEN1KMT2AGAAGFERIDO1 | |
| SCHEMBL17103022 | 0.84 | KMT2A (0.67) | MEN1KMT2AGAAGFERIDO1 | |
| SCHEMBL5037216 | 0.84 | KDM1A (0.69) | MEN1KMT2AGAAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230126893-A1 | [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS ACTIVE HERBICIDAL INGREDIENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20210120811-A1 | AQUEOUS CAPSULE SUSPENSION CONCENTRATES CONTAINING A HERBICIDAL SAFENER AND A PESTICIDAL ACTIVE SUBSTANCE | FMC CORPORATION | 2021-04-29 | — | — | US | disclosed |
| US-20200404916-A1 | METHOD OF REDUCING CROP DAMAGE | BAYER AKTIENGESELLSCHAFT (DE) | 2020-12-31 | — | — | US | disclosed |
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2020-12-17 | — | — | US | disclosed |
| US-20200181117-A1 | SUBSTITUTED 3-HETEROARYLOXY-1H-PYRAZOLES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL ACTIVE SUBSTANCES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-11 | — | — | US | disclosed |
| US-20200172491-A1 | SUBSTITUTED 5-(HET-)ARYLPYRAZOLAMIDES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL ACTIVE SUBSTANCES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | US | disclosed |
| US-20190330192-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-10-31 | — | — | US | disclosed |
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| EP-2219635-B1 | METHODS OF INHIBITING BACTERIAL VIRULENCE AND COMPOUNDS RELATING THERETO | UNIV TEXAS (US) | 2017-01-25 | — | — | EP | disclosed |
| CN-105801582-A | Novel dihydro pteridinone derivative, preparing method thereof and application to medicine | 合肥工业大学 | 2016-07-27 | — | — | CN | disclosed |
| US-8252841-B2 | Methods of inhibiting bacterial virulence and compounds relating thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-08-28 | — | — | US | disclosed |
| US-8252841-B2 | Methods of inhibiting bacterial virulence and compounds relating thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-08-28 | — | — | US | disclosed |
| US-8252841-B2 | Methods of inhibiting bacterial virulence and compounds relating thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2219635-A2 | METHODS OF INHIBITING BACTERIAL VIRULENCE AND COMPOUNDS RELATING THERETO | The Board of Regents of The University of Texas System (US) | 2010-08-25 | — | — | EP | disclosed |
| US-20100048573-A1 | Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2010-02-25 | — | — | US | disclosed |
| US-20100048573-A1 | Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2010-02-25 | — | — | US | disclosed |
| US-20100048573-A1 | Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2010-02-25 | — | — | US | disclosed |
| WO-2009088549-A2 | METHODS OF INHIBITING BACTERIAL VIRULENCE AND COMPOUNDS RELATING THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009088549-A2 | METHODS OF INHIBITING BACTERIAL VIRULENCE AND COMPOUNDS RELATING THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | DDT, NOTUM, AGPS | MEN1 3916/4885KMT2A 2086/4885GAA 985/4885 |
| US-20200172491-A1 | SUBSTITUTED 5-(HET-)ARYLPYRAZOLAMIDES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL ACTIVE SUBSTANCES | CYP4Z1, CYP3A5, CYP4X1 | MEN1 4463/4885KMT2A 1729/4885GAA 299/4885 |
| US-20200181117-A1 | SUBSTITUTED 3-HETEROARYLOXY-1H-PYRAZOLES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL ACTIVE SUBSTANCES | GLRX3, CYP4F3, AGXT | MEN1 4579/4885KMT2A 2052/4885GAA 449/4885 |
| US-20200404916-A1 | METHOD OF REDUCING CROP DAMAGE | DDT, GAP43, GSS | MEN1 4554/4885KMT2A 2281/4885GAA 784/4885 |
| US-20230126893-A1 | [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS ACTIVE HERBICIDAL INGREDIENTS | SYMPK, ALDH7A1, AADAC | MEN1 4564/4885KMT2A 2064/4885GAA 429/4885 |
| US-20210120811-A1 | AQUEOUS CAPSULE SUSPENSION CONCENTRATES CONTAINING A HERBICIDAL SAFENER AND A PESTICIDAL ACTIVE SUBSTANCE | DDT, DERL1, GMDS | MEN1 1620/4885KMT2A 352/4885GAA 2195/4885 |
| US-20190330192-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | AGPS, AASDHPPT, HPD | MEN1 2887/4885KMT2A 872/4885GAA 1566/4885 |
| US-20100048573-A1 | Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto | MMP8, SLC11A2, NFKBIA | MEN1 3468/4885KMT2A 4400/4885GAA 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.