Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514512 | 1.00 | PKM (0.53) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL9065707 | 0.85 | PKM (0.54) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL10544950 | 0.83 | PKM (0.60) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL9831364 | 0.83 | PKM (0.62) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL339943 | 0.83 | PKM (0.62) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL9829190 | 0.83 | PKM (0.62) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL29452841 | 0.83 | PKM (0.62) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL9245052 | 0.83 | PKM (0.62) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL9828540 | 0.83 | PKM (0.56) | PKMKDM4EALOX12TDP1CYP3A4 | |
| SCHEMBL4902562 | 0.82 | PKM (0.60) | PKMKDM4EALOX12TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| EP-1771067-B1 | SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2014-03-12 | — | — | EP | claimed |
| EP-1855529-B1 | SPIROKETAL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-12-18 | — | — | EP | claimed |
| EP-1966135-B1 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2013-10-09 | — | — | EP | claimed |
| US-8507537-B2 | Trifluromethoxyphenyl-substituted tetramic acid derivatives pesticides and/or herbicides | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | claimed |
| US-7115543-B2 | Aryl sulfonyl amino carbonyl triazole based selective herbicides | BAYER CROPSCIENCE AG (DE) | 2006-10-03 | — | — | US | claimed |
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | claimed |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | claimed |
| US-20060160703-A1 | Selective herbicides based on substituted cyclic dicarbonyl compounds and safeners | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | claimed |
| EP-1303189-B1 | ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2005-08-24 | — | — | EP | claimed |
| US-20050054535-A1 | Selective herbicides based on substituted cyclic keto-enols and safeners | BAYER CROPSCIENCE AG (DE) | 2005-03-10 | — | — | US | claimed |
| US-20050009705-A1 | Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | US | claimed |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | BAYER CROPSCIENCE K.K. (JP) | 2004-07-08 | — | — | US | claimed |
| US-20030211942-A1 | Aryl sulfonyl amino carbonyl triazole based selective herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-11-13 | — | — | US | claimed |
| US-5488027-A | Herbicide-safener combinations containing sulfonylurea or imidazolinone herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | WEE1, KCNE1, CCNE1 | PKM 12/4885KDM4E 22/4885ALOX12 1443/4885 |
| US-20030211942-A1 | Aryl sulfonyl amino carbonyl triazole based selective herbicides | AADAC, CBR3, ABAT | PKM 921/4885KDM4E 1867/4885ALOX12 2886/4885 |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | CYP2W1, CYP4Z1, CYP2E1 | PKM 450/4885KDM4E 1001/4885ALOX12 1017/4885 |
| US-20050009705-A1 | Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners | TARS2, TST, DDT | PKM 1520/4885KDM4E 2555/4885ALOX12 3169/4885 |
| US-20060160703-A1 | Selective herbicides based on substituted cyclic dicarbonyl compounds and safeners | DDT, DDX41, DDC | PKM 1425/4885KDM4E 627/4885ALOX12 3144/4885 |
| US-20050054535-A1 | Selective herbicides based on substituted cyclic keto-enols and safeners | DDT, LAGE3, KYAT1 | PKM 33/4885KDM4E 22/4885ALOX12 2506/4885 |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | PKM 1663/4885KDM4E 2075/4885ALOX12 1253/4885 |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | DDT, DDC, DAO | PKM 306/4885KDM4E 2868/4885ALOX12 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.