Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559719 | 0.95 | ALDH1A1 (0.62) | SMN1; SMN2NOTUMALDH1A1KDM4EPOLB | |
| SCHEMBL1928973 | 0.90 | TSHR (0.75) | SMN1; SMN2NOTUMALDH1A1POLBTSHR | |
| SCHEMBL29770335 | 0.90 | TSHR (0.75) | SMN1; SMN2NOTUMALDH1A1POLBTSHR | |
| SCHEMBL5251752 | 0.88 | TSHR (0.67) | SMN1; SMN2NOTUMALDH1A1KDM4EPOLB | |
| SCHEMBL1545217 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2NOTUMALDH1A1KDM4EPOLB | |
| SCHEMBL1764033 | 0.85 | TSHR (0.72) | SMN1; SMN2NOTUMALDH1A1KDM4EPOLB | |
| SCHEMBL25391399 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2NOTUMALDH1A1KDM4EPOLB | |
| SCHEMBL3089154 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2NOTUMALDH1A1KDM4EPOLB | |
| SCHEMBL30253474 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2NOTUMALDH1A1KDM4EPOLB | |
| SCHEMBL29520673 | 0.84 | NOTUM (0.69) | SMN1; SMN2NOTUMALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102285915-B | Synthesis method for alkaloid secondary metabolite aspernigerin having anticancer activity | UNIV CHINA AGRICULTURAL | 2014-04-02 | — | — | CN | claimed |
| US-12295368-B2 | Method for controlling hematophagous or sap-feeding arthropods | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSTIY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2025-05-13 | — | — | US | disclosed |
| US-20240024318-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20230276802-A1 | Method for Controlling Hematophagous or Sap-Feeding Arthropods | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSTIY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| US-20230190940-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20230190940-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-22 | — | — | US | disclosed |
| US-11679109-B2 | SMARCA degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-7166617-B2 | Cyclic amide derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20060270688-A1 | Compounds for modulating TRPV3 function | HYDRA BIOSCIENCES, INC. (US) | 2006-11-30 | — | — | US | disclosed |
| US-20030212094-A1 | Novel cyclic amide derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1260512-A1 | NOVEL CYCLIC AMIDE DERIVATIVES | Mitsubishi Pharma Corporation (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0147805-B1 | SPIRO-LINKED PYRROLIDINE-2,5-DIONES AND PROCESS FOR THEIR PREPARATION | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-10-10 | — | — | EP | disclosed |
| US-4593092-A | Spiro-linked pyrrolidin-2,5-dione | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-06-03 | — | — | US | disclosed |
| EP-0147805-A2 | Spiro-linked pyrrolidine-2,5-diones and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1985-07-10 | — | — | EP | disclosed |
| US-4137065-A | HERBICIDE, INSECTICIDE, NEMATOCIDE, MITICIDE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1979-01-30 | — | — | US | disclosed |
| US-4099954-A | Amide phosphorothiolate herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-07-11 | — | — | US | disclosed |
| US-3997526-A | HERBICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270688-A1 | Compounds for modulating TRPV3 function | TRPV3, TRPV1, TRPV4 | SMN1; SMN2 2219/4885NOTUM 3883/4885ALDH1A1 3074/4885 |
| US-20230234953-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | SMN1; SMN2 2647/4885NOTUM 1368/4885ALDH1A1 2776/4885 |
| US-20240024318-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | SMN1; SMN2 716/4885NOTUM 1878/4885ALDH1A1 2230/4885 |
| US-20030212094-A1 | Novel cyclic amide derivatives | SIGMAR1, OPRM1, OPRD1 | SMN1; SMN2 4778/4885NOTUM 1388/4885ALDH1A1 690/4885 |
| US-20230190940-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | SMN1; SMN2 2647/4885NOTUM 1368/4885ALDH1A1 2776/4885 |
| US-11679109-B2 | SMARCA degraders and uses thereof | SMARCA1, SMARCA2, SMARCC2 | SMN1; SMN2 716/4885NOTUM 1878/4885ALDH1A1 2230/4885 |
| US-12295368-B2 | Method for controlling hematophagous or sap-feeding arthropods | KCNN1, KCNN2, KCNN3 | SMN1; SMN2 3766/4885NOTUM 2264/4885ALDH1A1 3871/4885 |
| US-20230276802-A1 | Method for Controlling Hematophagous or Sap-Feeding Arthropods | KCNN1, KCNN2, KCNN3 | SMN1; SMN2 3766/4885NOTUM 2264/4885ALDH1A1 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.