SCHEMBL3429762

SCHEMBL3429762

Cc1cccc(B2OC(C)(C)C(C)(C)O2)c1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 14/20 0.53
LPL P06858 13/20 0.53
IRAK4 Q9NWZ3 1/20 0.43
ACHE P22303 1/20 0.42
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
CSF1R P07333 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29591441 1.00 LIPG (0.53) LIPGLPLIRAK4ACHEALDH1A1
SCHEMBL25626105 0.89 LIPG (0.51) LIPGLPLIRAK4ACHEALDH1A1
SCHEMBL20026486 0.88 LIPG (0.50) LIPGLPLIRAK4ACHEALDH1A1
SCHEMBL1476213 0.87 LIPG (0.59) LIPGLPLIRAK4CA1CA2
SCHEMBL16460597 0.87 LIPG (0.49) LIPGLPLIRAK4CA1CA2
SCHEMBL22867772 0.82 POLB (0.44) LIPGLPLALDH1A1HPGD
SCHEMBL806784 0.82 LIPG (0.60) LIPGLPLIRAK4CA1CA2
SCHEMBL23956366 0.80 LIPG (0.69) LIPGLPLCA1CA2CA9
SCHEMBL18621848 0.80 LIPG (0.59) LIPGLPLIRAK4KDM4EMAPT
SCHEMBL12715045 0.80 LIPG (0.50) LIPGLPLIRAK4ACHEHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-20250186391-A1 ORAL COMPLEMENT FACTOR D INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-06-12 US disclosed
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2024-07-18 US disclosed
WO-2024144190-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 솔루스첨단소재 주식회사 2024-07-04 WO disclosed
US-20240150293-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS VERNALIS (R&D) LTD (GB) 2024-05-09 US disclosed
EP-3929194-B1 SUBSTITUTED NITROGEN CONTAINING COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2024-04-17 EP disclosed
US-11917906-B2 Compounds that can be used in an organic electronic device MERCK PATENT GMBH (DE) 2024-02-27 US disclosed
US-11912710-B2 Substituted pyrimido[4,5-b][1,4]diazepines as PLK1 degradation inducers UPPTHERA, INC. (KR) 2024-02-27 US disclosed
US-11912710-B2 Substituted pyrimido[4,5-b][1,4]diazepines as PLK1 degradation inducers UPPTHERA, INC. (KR) 2024-02-27 US disclosed
US-11912710-B2 Substituted pyrimido[4,5-b][1,4]diazepines as PLK1 degradation inducers UPPTHERA, INC. (KR) 2024-02-27 US disclosed
WO-2012129491-A1 TRPV3 MODULATORS ABBOTT LABORATORIES (US) 2012-09-27 WO disclosed
US-20120184768-A1 PREPARATION METHOD OF AROMATIC BORONATE COMPOUNDS PEKING UNIVERSITY (CN) 2012-07-19 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
US-7943618-B2 Btk protein kinase inhibitors ROCHE PALO ALTO LLC (US) 2011-05-17 US disclosed
EP-2249830-A1 DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS Glaxo Group Limited (GB) 2010-11-17 EP disclosed
WO-2010077992-A1 AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS AMGEN INC. (US) 2010-07-08 WO disclosed
US-20100160280-A1 AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS AMGEN INC. (US) 2010-06-24 US disclosed
US-20100160280-A1 AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS AMGEN INC. (US) 2010-06-24 US disclosed
WO-2009100170-A1 DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS GLAXO GROUP LIMITED (GB) 2009-08-13 WO disclosed
US-20090105209-A1 BTK protein kinase inhibitors ROCHE PALO ALTO LLC 2009-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150293-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BAX, BCL2A1 LIPG 2561/4885LPL 3805/4885IRAK4 2891/4885
US-20090105209-A1 BTK protein kinase inhibitors BTK, SYK, LYN LIPG 3362/4885LPL 3465/4885IRAK4 9/4885
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 LIPG 2586/4885LPL 3121/4885IRAK4 629/4885
US-12558341-B2 Oral complement factor D inhibitors CFD, CFH, CFB LIPG 511/4885LPL 263/4885IRAK4 3523/4885
US-20120184768-A1 PREPARATION METHOD OF AROMATIC BORONATE COMPOUNDS AHR, BLVRB, AR LIPG 3859/4885LPL 4008/4885IRAK4 1311/4885
US-20100160280-A1 AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS PDE4A, PDE7A, PDE4D LIPG 3721/4885LPL 2887/4885IRAK4 872/4885
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS HAO2, SCO2, SOD1 LIPG 1232/4885LPL 2814/4885IRAK4 4719/4885
US-20250186391-A1 ORAL COMPLEMENT FACTOR D INHIBITORS CFD, CFH, CFB LIPG 357/4885LPL 612/4885IRAK4 2027/4885
US-11912710-B2 Substituted pyrimido[4,5-b][1,4]diazepines as PLK1 degradation inducers PLK1, BUB1B, BUB1 LIPG 3577/4885LPL 3731/4885IRAK4 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.