SCHEMBL343190

SCHEMBL343190

CCOC(=O)NC(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 1/20 0.41
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
CA1 P00915 2/20 0.41
CA7 P43166 2/20 0.41
CA12 O43570 2/20 0.41
CA14 Q9ULX7 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
CA2 P00918 2/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7713280 0.83 GAA (0.55) CYP1A2CYP2C9CYP2C19ALDH1A1GAA
SCHEMBL101218 0.83 DGAT1 (0.46) MEN1KMT2AGAACA1CA7
SCHEMBL3403411 0.83 APLNR (0.49) CYP1A2CYP2C9CYP2C19HTTALDH1A1
SCHEMBL1294994 0.82 EGLN1 (0.44) CYP1A2CYP2C9CYP2C19HTTALDH1A1
Potassium SCHEMBL29554503 0.81 DGAT1 (0.44) MEN1KMT2AGAACA1CA7
SCHEMBL1522412 0.81 DGAT1 (0.44) MEN1KMT2AGAACA1CA7
SCHEMBL6272856 0.81 DGAT1 (0.44) MEN1KMT2AGAACA1CA7
SCHEMBL28895815 0.81 TDP1 (0.39) MEN1KMT2AGAACA1CA7
SCHEMBL15228762 0.80 GAA (0.50) CYP1A2CYP2C9CYP2C19HTTALDH1A1
SCHEMBL27907267 0.80 EPHX1 (0.47) ALDH1A1CA1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3177601-B1 TLR-INDEPENDENT SMALL MOLECULE ADJUVANTS SCRIPPS RESEARCH INST (US) 2023-03-01 EP disclosed
US-20200300843-A1 Clozapine Immunoassay SALADAX BIOMEDICAL INC (US) 2020-09-24 US disclosed
EP-2714920-B1 CLOZAPINE IMMUNOASSAY SALADAX BIOMEDICAL INC (US) 2018-05-02 EP disclosed
US-9551724-B2 5-fluoro-uracil immunoassay SALADAX BIOMEDICAL, INC. (US) 2017-01-24 US disclosed
EP-1774331-B1 CYTOXAN ANTIBODIES AND IMMUNOASSAY SALADAX BIOMEDICAL INC (US) 2015-09-02 EP disclosed
US-20150104818-A1 GEMCITABINE IMMUNOASSAY SALADAX BIOMEDICAL INC. 2015-04-16 US disclosed
EP-2544540-B1 LENALIDOMIDE AND THALIDOMIDE IMMUNOASSAYS SALADAX BIOMEDICAL INC (US) 2015-04-08 EP disclosed
US-8946392-B2 Gemcitabine immunoassay SALADAX BIOMEDICAL INC. (US) 2015-02-03 US disclosed
US-20140302618-A1 Clozapine Immunoassay SALADAX BIOMEDICAL INC. (US) 2014-10-09 US disclosed
US-20140273023-A1 GEMCITABINE IMMUNOASSAY SALADAX BIOMEDICAL INC. (US) 2014-09-18 US disclosed
US-20010007877-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION 2001-07-12 US disclosed
WO-2001034146-A1 NOVEL ANTI-INFECTIVES SMITHKLINE BEECHAM CORPORATION (US) 2001-05-17 WO disclosed
EP-0399184-B1 Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay ABBOTT LAB (US) 1995-09-13 EP disclosed
US-5354693-A Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassy ABBOTT LABORATORIES (US) 1994-10-11 US disclosed
US-5248791-A Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1993-09-28 US disclosed
US-5101015-A Nitrogen-functional-group-containing immunogen ABBOTT LABORATORIES (US) 1992-03-31 US disclosed
EP-0399184-A2 Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1990-11-28 EP disclosed
US-4193917-A LACTAM COMPOUND USED AS INTERMEDIATE GLAXO LABORATORIES, LIMITED (GB) 1980-03-18 US disclosed
US-4174318-A USING A TRIALKYL- OR TRIALKYLAMINOPHOSPHINE AS REDUCING AGENT GLAXO LABORATORIES LTD. (GB) 1979-11-13 US disclosed
US-4014872-A ANTIBIOTICS GLAXO LABORATORIES LIMITED (EN) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140273023-A1 GEMCITABINE IMMUNOASSAY SAMHD1, GMNN, GEMIN5 CYP1A2 3742/4885CYP2C9 3162/4885CYP2C19 4014/4885
US-20150104818-A1 GEMCITABINE IMMUNOASSAY GMNN, GNG2, GEMIN4 CYP1A2 4542/4885CYP2C9 4498/4885CYP2C19 4720/4885
US-20200300843-A1 Clozapine Immunoassay GAP43, CHAT, PA2G4 CYP1A2 371/4885CYP2C9 1040/4885CYP2C19 724/4885
US-20140302618-A1 Clozapine Immunoassay GAP43, CHAT, PA2G4 CYP1A2 371/4885CYP2C9 1040/4885CYP2C19 724/4885
US-20010007877-A1 NOVEL ANTI-INFECTIVES CTSL, MMP8, SERPINB1 CYP1A2 4409/4885CYP2C9 4367/4885CYP2C19 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.