Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.35 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489803 | 0.97 | CA4 (0.32) | CA4 | |
| SCHEMBL5354738 | 0.97 | — | — | |
| SCHEMBL5014722 | 0.74 | ALDH1A1 (0.35) | CA1 | |
| SCHEMBL5714066 | 0.73 | CA4 (0.42) | CA4CA1 | |
| SCHEMBL6257442 | 0.70 | — | — | |
| SCHEMBL27912772 | 0.69 | — | — | |
| SCHEMBL6443543 | 0.69 | ALDH1A1 (0.35) | CA1 | |
| SCHEMBL6859549 | 0.68 | ALDH1A1 (0.41) | CA4CA1 | |
| SCHEMBL1898315 | 0.68 | — | — | |
| Ammonia Solution, Strong SCHEMBL2306787 | 0.67 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869817-B2 | Antiperspirant stick compositions | Henkel IP & Holding GmbH | 2020-12-22 | — | — | US | claimed |
| US-10835483-B2 | Antiperspirant stick compositions | Henkel IP & Holding GmbH | 2020-11-17 | — | — | US | claimed |
| US-10821068-B2 | Antiperspirant stick compositions | Henkel IP & Holding GmbH (DE) | 2020-11-03 | — | — | US | claimed |
| EP-3694473-A1 | ANTIPERSPIRANT STICK COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2020-08-19 | — | — | EP | claimed |
| WO-2019074643-A1 | ANTIPERSPIRANT STICK COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2019-04-18 | — | — | WO | claimed |
| WO-2019074647-A1 | ANTIPERSPIRANT STICK COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2019-04-18 | — | — | WO | claimed |
| US-20190105256-A1 | ANTIPERSPIRANT STICK COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2019-04-11 | — | — | US | claimed |
| US-20190105239-A1 | ANTIPERSPIRANT STICK COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2019-04-11 | — | — | US | claimed |
| US-20190105255-A1 | ANTIPERSPIRANT STICK COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2019-04-11 | — | — | US | claimed |
| US-20190105257-A1 | ANTIPERSPIRANT STICK COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2019-04-11 | — | — | US | claimed |
| WO-2015055199-A2 | ANTIPERSPIRANT COSMETIC AGENTS HAVING ALPHA-HYDROXY ACIDS | HENKEL AG & CO. KGAA (DE) | 2015-04-23 | — | — | WO | claimed |
| WO-2015055197-A1 | ANTIPERSPIRANT COSMETIC AGENTS HAVING POLYPHOSPHORIC ACIDS | HENKEL AG & CO. KGAA (DE) | 2015-04-23 | — | — | WO | claimed |
| WO-2015055198-A1 | COSMETIC ANTIPERSPIRANTS WITH AROMATIC SULPHONIC ACIDS | HENKEL AG & CO. KGAA (DE) | 2015-04-23 | — | — | WO | claimed |
| WO-2015055184-A1 | COSMETIC ANTIPERSPIRANTS WITH LACTATES | HENKEL AG & CO. KGAA (DE) | 2015-04-23 | — | — | WO | claimed |
| WO-2015055196-A2 | ANTIPERSPIRANT COSMETIC AGENTS HAVING POLYCARBOXYLIC ACIDS | HENKEL AG & CO. KGAA (DE) | 2015-04-23 | — | — | WO | claimed |
| EP-0972512-B1 | Cosmetic composition containing pigments, an antiperspirant and a solid elastomeric partially crosslinked organopolysiloxane, use of such a composition | OREAL (FR) | 2002-01-02 | — | — | EP | claimed |
| US-6251412-B1 | USE IN MAKE-UP, TO IMPROVE THE STAYING POWER OF THE COLOR OF THE COMPOSITION | L'OREAL (FR) | 2001-06-26 | — | — | US | claimed |
| EP-0318206-A1 | Deodorant gel stick | THE PROCTER & GAMBLE COMPANY (US) | 1989-05-31 | — | — | EP | claimed |
| US-4816261-A | Deodorant gel stick | THE PROCTER & GAMBLE COMPANY (US) | 1989-03-28 | — | — | US | claimed |
| US-4781917-A | FREE OF UNBOUND WATER | THE PROCTOR & GAMBLE COMPANY (US) | 1988-11-01 | — | — | US | claimed |