SCHEMBL345445

SCHEMBL345445

CC(C)c1ccc(N(CCO)CCO)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.49
ERBB2 P04626 1/20 0.49
SMN1; SMN2 Q16637 5/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 3/20 0.49
TP53 P04637 1/20 0.49
ATM Q13315 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MAPT P10636 3/20 0.42
MEN1 O00255 2/20 0.42
HTT P42858 2/20 0.42
GAA P10253 2/20 0.42
PKM P14618 1/20 0.42
MCL1 Q07820 1/20 0.42
HPGD P15428 3/20 0.39
CNR2 P34972 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ALDH1A1 P00352 3/20 0.37
TSHR P16473 1/20 0.37
TYR P14679 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10152990 0.90 CNR2 (0.45) EGFRERBB2SMN1; SMN2KMT2ALMNA
SCHEMBL16082902 0.88 KMT2A (0.45) EGFRERBB2SMN1; SMN2KMT2ALMNA
SCHEMBL3893912 0.83 KMT2A (0.56) EGFRERBB2SMN1; SMN2KMT2ALMNA
SCHEMBL6243535 0.82 MAPT (0.44) EGFRERBB2SMN1; SMN2KMT2ALMNA
SCHEMBL6782387 0.82 L3MBTL1 (0.55) EGFRERBB2SMN1; SMN2KMT2ALMNA
SCHEMBL17531379 0.81 CNR2 (0.43) EGFRERBB2SMN1; SMN2KMT2ALMNA
SCHEMBL12056655 0.81 EGFR (0.46) EGFRERBB2SMN1; SMN2KMT2ANPSR1
Hydrochloric Acid SCHEMBL8038931 0.79 MAPT (0.43) EGFRERBB2SMN1; SMN2KMT2ALMNA
SCHEMBL345442 0.79 KMT2A (0.38) EGFRERBB2SMN1; SMN2KMT2ALMNA
SCHEMBL21146474 0.79 KMT2A (0.49) EGFRERBB2SMN1; SMN2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 539 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552299-A Method for realizing anti-caking of acrylic resin powder 博立尔化工(扬州)有限公司 2025-03-04 CN claimed
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION TROETSCHLER TOBIAS (DE) 2026-05-07 US disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
EP-4736833-A1 POLYMERIZABLE DENTAL COMPOSITION DENTSPLY SIRONA Inc. (US) 2026-05-06 EP disclosed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
US-6410612-B1 ACRYLIC POLYMER BLEND KURARAY CO., LTD. (JP) 2002-06-25 US disclosed
US-20020035169-A1 Bonding compositions for dental use KURARAY CO., LTD (JP) 2002-03-21 US disclosed
US-6355704-B1 BACTERICIDE PRIMERS; BONDING TO TEETH KURARAY CO., LTD. (JP) 2002-03-12 US disclosed
US-20020016417-A1 Fitting composition, body-worn tool produced using the same, and method for producing the same KURARAY CO., LTD (JP) 2002-02-07 US disclosed
EP-1167408-A1 Fitting composition, body-worn tool produced using the same, and method for producing the same Kuraray Co., Ltd. (JP) 2002-01-02 EP disclosed
US-6191191-B1 USED AS BONDING AGENT, COMPOSITE RESIN, ADHESIVE AGENT, PRIMER AND OPAQUE PRIMER FOR DENTAL USE; LIGHT RESISTANCE; ADHESION TO TOOTH SURFACE AND METALS; COLORFASTNESS KURARAY CO., LTD. (JP) 2001-02-20 US disclosed
EP-1057468-A1 Adhesive composition and method for producing it KURARAY CO., LTD. (JP) 2000-12-06 EP disclosed
EP-1033125-A1 Relining material for dentures KURARAY CO., LTD. (JP) 2000-09-06 EP disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed
EP-0948955-A1 POLYMERIZABLE DENTAL COMPOSITION KURARAY CO., LTD. (JP) 1999-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035169-A1 Bonding compositions for dental use PTK2, DEK, POLK EGFR 2875/4885ERBB2 1638/4885SMN1; SMN2 3319/4885
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 EGFR 2961/4885ERBB2 2649/4885SMN1; SMN2 3231/4885
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL CAD, KIT, ILK EGFR 4452/4885ERBB2 3882/4885SMN1; SMN2 2114/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A EGFR 4327/4885ERBB2 3877/4885SMN1; SMN2 2674/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 EGFR 4071/4885ERBB2 2921/4885SMN1; SMN2 2498/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL EGFR 3643/4885ERBB2 3242/4885SMN1; SMN2 2292/4885
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION F12, RAD51, PFN1 EGFR 4243/4885ERBB2 4164/4885SMN1; SMN2 2706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.