Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454570 | 0.81 | NMT1 (0.33) | PLATHTR6 | |
| SCHEMBL3456235 | 0.76 | GPR119 (0.36) | — | |
| SCHEMBL3454499 | 0.72 | HTR6 (0.33) | RORCPLATJAK2HTR6 | |
| SCHEMBL22324769 | 0.68 | SLC18A3 (0.48) | RORCHTR6 | |
| SCHEMBL3454488 | 0.68 | CNR2 (0.34) | CNR2RORCPLATJAK2HTR6 | |
| SCHEMBL3072064 | 0.65 | SYK (0.44) | RORCPLATJAK2HTR6 | |
| SCHEMBL3468776 | 0.61 | OPRD1 (0.48) | — | |
| SCHEMBL4777240 | 0.61 | GBA1 (0.54) | CNR2RORCHTR6 | |
| Hydrochloric Acid SCHEMBL4773264 | 0.60 | GBA1 (0.53) | CNR2RORCHTR6 | |
| SCHEMBL5051360 | 0.59 | RORC (0.60) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166850-A1 | NEW HETEOCYCLIC H3 ANTAGONISTS | High Point Pharmaceuticals, LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154126-A1 | NEW HETEOCYCLIC H3 ANTAGONISTS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2008-12-18 | — | — | WO | disclosed |