Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzophenone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 4/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histamine SCHEMBL8789327 | 0.88 | HRH1 (0.37) | KMT2AMEN1KDM4EHPGDSMN1; SMN2 | |
| Histamine SCHEMBL1782847 | 0.85 | HRH4 (0.36) | HRH1TDP1 | |
| Phthalic Acid SCHEMBL5769935 | 0.85 | HMGB1 (0.43) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| Histamine SCHEMBL11855302 | 0.84 | HRH1 (0.36) | ALDH1A1RAB9ASMN1; SMN2HRH1 | |
| Histamine SCHEMBL28074178 | 0.83 | HRH1 (0.42) | SMN1; SMN2HRH1TDP1 | |
| Histamine SCHEMBL4234179 | 0.83 | HRH4 (0.39) | SMN1; SMN2HRH1TDP1 | |
| Histamine SCHEMBL8571326 | 0.83 | HRH1 (0.42) | ALDH1A1KMT2AKDM4ESMN1; SMN2HRH1 | |
| Histamine SCHEMBL8847483 | 0.83 | HRH1 (0.33) | HRH1 | |
| Histamine SCHEMBL8887482 | 0.82 | HRH4 (0.34) | HRH1TDP1 | |
| Histamine SCHEMBL5840054 | 0.82 | HRH4 (0.38) | HRH1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932851-B1 | METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE | SUMITOMO CHEMICAL CO (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-20120211706-A1 | POLYDENTATE LIGAND METAL COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-23 | — | — | US | disclosed |
| US-20100264812-A1 | METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-1932851-A1 | METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE | Sumitomo Chemical Company, Limited (JP) | 2008-06-18 | — | — | EP | disclosed |
| CN-1095829-C | Removel of water and ammoia from benzophenone imine reactor effluents | BASF AG (DE) | 2002-12-11 | — | — | CN | disclosed |
| CN-1180070-A | Removel of water and ammoia from benzophenone imine reactor effluents | BASFF AG (DE) | 1998-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120211706-A1 | POLYDENTATE LIGAND METAL COMPLEX | CAD, SLC7A5, PICALM | HRH1 2512/4885ALDH1A1 4876/4885KMT2A 1617/4885 |
| US-20100264812-A1 | METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE | SOD1, CRY1, YAP1 | HRH1 496/4885ALDH1A1 2442/4885KMT2A 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.