SCHEMBL345962

SCHEMBL345962

Cc1cccc(C)c1P(=O)(C(=O)c1ccccc1)c1c(C)cccc1C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.46
POLB P06746 2/20 0.46
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
KCNK3 O14649 1/20 0.41
KCNK9 Q9NPC2 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
EPHX1 P07099 1/20 0.39
ELANE P08246 1/20 0.39
HSP90AA1 P07900 1/20 0.38
DAO P14920 1/20 0.38
TSHR P16473 1/20 0.38
NAPRT Q6XQN6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989034 0.91 HPGD (0.46) HPGDPOLBALDH1A1L3MBTL1ATM
SCHEMBL20512976 0.85 SMN1; SMN2 (0.42) HPGDPOLBALDH1A1L3MBTL1ATM
SCHEMBL2771670 0.80 NR1H4 (0.40) HPGDPOLBALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL988213 0.78 POLB (0.40) HPGDPOLBALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL37050 0.78 LMNA (0.40) HPGDPOLBSMN1; SMN2CES2CES1
SCHEMBL8514991 0.77 HPGD (0.46) HPGDPOLBALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL711235 0.77 SMN1; SMN2 (0.46) HPGDPOLBALDH1A1L3MBTL1ATM
SCHEMBL6383471 0.74 KMT2A (0.38) HPGDSMN1; SMN2
SCHEMBL2771466 0.74 KMT2A (0.44) HPGDPOLBALDH1A1SMN1; SMN2CES2
SCHEMBL7182450 0.73 FABP3 (0.39) HPGDPOLBALDH1A1SMN1; SMN2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
US-20250032366-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-30 US disclosed
EP-3646847-B1 TWO-PASTE TYPE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2025-01-29 EP disclosed
WO-2024253204-A1 CURABLE DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-12-12 WO disclosed
EP-4445891-A1 DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-10-16 EP disclosed
CN-118338879-A Curable composition for dental use 可乐丽则武齿科株式会社 2024-07-12 CN disclosed
WO-2023106419-A1 DENTAL CURABLE COMPOSITION クラレノリタケデンタル株式会社 2023-06-15 WO disclosed
CN-110785159-B Dual paste type curable dental composition 可乐丽则武齿科株式会社 2023-06-09 CN disclosed
US-20230049373-A1 PASTE-LIKE COMPOSITION FOR DENTAL USE, AND METHOD FOR PRODUCING THE SAME KURARAY NORITAKE DENTAL INC. (JP) 2023-02-16 US disclosed
CN-112940432-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2022-12-30 CN disclosed
EP-2409997-A1 REDOX-CURING TYPE COMPOSITION Kuraray Medical Inc. (JP) 2012-01-25 EP disclosed
US-20120016094-A1 REDOX-CURING TYPE COMPOSITION KURARAY MEDICAL INC. (JP) 2012-01-19 US disclosed
US-20100087613-A1 DIVIDED REDOX-CURING TYPE COMPOSITION KURARAY MEDICAL INC. (JP) 2010-04-08 US disclosed
EP-2110392-A1 MULTI-PART REDOX-CURING-TYPE COMPOSITION Kuraray Medical Inc. (JP) 2009-10-21 EP disclosed
US-20090068123-A1 FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES KURARAY MEDICAL INC (JP) 2009-03-12 US disclosed
EP-1864645-A1 FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES Kuraray Medical Inc. (JP) 2007-12-12 EP disclosed
EP-1236459-B1 PHOTO-CURABLE REPARATIVE MATERIAL FOR DENTAL USE TOKUYAMA CORP (JP) 2005-11-23 EP disclosed
US-6849670-B2 Photo-curable reparative material for dental use TOKUYAMA CORPORATION (JP) 2005-02-01 US disclosed
US-20030162863-A1 Photo-curable reparative material for dental use TOKUYAMA CORPORATION (JP) 2003-08-28 US disclosed
EP-1236459-A1 PHOTO-CURABLE REPARATIVE MATERIAL FOR DENTAL USE TOKUYAMA CORPORATION (JP) 2002-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032366-A1 DENTAL CURABLE COMPOSITION H1-0, COL1A1, CHAF1B HPGD 2520/4885POLB 1654/4885ALDH1A1 1530/4885
US-20090068123-A1 FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES ITGA5, ITGAL, PHOSPHO1 HPGD 4465/4885POLB 3824/4885ALDH1A1 3682/4885
US-20030162863-A1 Photo-curable reparative material for dental use MBTD1, AP3M1, MYO1G HPGD 3210/4885POLB 737/4885ALDH1A1 1806/4885
US-20230049373-A1 PASTE-LIKE COMPOSITION FOR DENTAL USE, AND METHOD FOR PRODUCING THE SAME PFN1, XRN2, FLNA HPGD 3548/4885POLB 596/4885ALDH1A1 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.