SCHEMBL346522

SCHEMBL346522

C1CCN(COCOCN2CCCCC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 2/20 0.35
CHRM5 P08912 1/20 0.35
ADRA2C P18825 1/20 0.35
MAPT P10636 2/20 0.33
ALDH1A1 P00352 3/20 0.32
GAA P10253 2/20 0.32
POLB P06746 1/20 0.32
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL17888871 0.97 HRH3 (0.38) HRH3MEN1KMT2ALMNACHRM5
SCHEMBL347313 0.97 LMNA (0.36) HRH3MEN1KMT2ALMNACHRM5
Hydrogen Sulfide SCHEMBL17888864 0.94 LMNA (0.35) HRH3MEN1KMT2ALMNA
SCHEMBL346747 0.88 HRH3 (0.43) HRH3MEN1KMT2ALMNACHRM5
SCHEMBL347464 0.84 LMNA (0.40) HRH3MEN1KMT2ALMNACHRM5
SCHEMBL20404160 0.79 PSMB1 (0.31) HRH3ALDH1A1
SCHEMBL2016344 0.78 HRH3 (0.36) HRH3MEN1KMT2ALMNACHRM5
SCHEMBL6684238 0.78 HRH3 (0.36) HRH3MEN1KMT2ALMNACHRM5
SCHEMBL6684244 0.78 MEN1 (0.39) HRH3MEN1KMT2ALMNACHRM5
SCHEMBL6684236 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593533-B1 USE OF ALPHA-AMINO ETHERS FOR THE REMOVAL OF MERCAPTANS FROM HYDROCARBONS NALCO CO (US) 2016-07-06 EP claimed
EP-2593533-A2 USE OF ALPHA-AMINO ETHERS FOR THE REMOVAL OF MERCAPTANS FROM HYDROCARBONS Nalco Company (US) 2013-05-22 EP claimed
US-20120012505-A1 USE OF ALPHA-AMINO ETHERS FOR THE REMOVAL OF MERCAPTANS FROM HYDROCARBONS NALCO COMPANY 2012-01-19 US claimed
WO-2012009390-A2 USE OF ALPHA-AMINO ETHERS FOR THE REMOVAL OF MERCAPTANS FROM HYDROCARBONS NALCO COMPANY (US) 2012-01-19 WO claimed
EP-3476478-B1 METHOD FOR REMOVING A SULFUR-CONTAINING COMPOUND KURARAY CO (JP) 2023-04-26 EP disclosed
CN-109310982-B Composition for removing sulfur-containing compounds 株式会社可乐丽(JP) 2023-01-13 CN disclosed
US-11291947-B2 Composition for removing sulfur-containing compound KURARAY CO., LTD. (JP) 2022-04-05 US disclosed
US-20190329175-A1 COMPOSITION FOR REMOVING SULFUR-CONTAINING COMPOUND KURARAY CO., LTD. (JP) 2019-10-31 US disclosed
EP-3252129-B1 COMPOSITION FOR REMOVING SULFUR-CONTAINING COMPOUNDS KURARAY CO (JP) 2019-08-14 EP disclosed
US-10294428-B2 Composition for removing sulfur-containing compounds KURARAY CO., LTD. (JP) 2019-05-21 US disclosed
EP-3121251-B1 REMOVAL OF SULPHUR-CONTAINING COMPOUNDS KURARAY CO (JP) 2019-05-08 EP disclosed
EP-3476478-A1 COMPOSITION FOR REMOVING SULFUR-CONTAINING COMPOUND Kuraray Co., Ltd. (JP) 2019-05-01 EP disclosed
US-9108899-B2 Sulfide scavengers, methods for making and methods for using GENERAL ELECTRIC COMPANY (US) 2015-08-18 US disclosed
US-8663457-B2 Methods and compounds for improving sulfide scavenging activity GENERAL ELECTRIC COMPANY (US) 2014-03-04 US disclosed
US-20130172623-A1 SULFIDE SCAVENGERS, METHODS FOR MAKING AND METHODS FOR USING GENERAL ELECTRIC COMPANY (US) 2013-07-04 US disclosed
US-20130126429-A1 AMINE SULFIDE SCAVENGERS, METHODS OF USING, AND METHODS OF MAKING GENERAL ELECTRIC COMPANY (US) 2013-05-23 US disclosed
US-20130131387-A1 METHODS AND COMPOUNDS FOR IMPROVING SULFIDE SCAVENGING ACTIVITY GENERAL ELECTRIC COMPANY (US) 2013-05-23 US disclosed
EP-2593533-A2 USE OF ALPHA-AMINO ETHERS FOR THE REMOVAL OF MERCAPTANS FROM HYDROCARBONS Nalco Company (US) 2013-05-22 EP disclosed
US-20120012505-A1 USE OF ALPHA-AMINO ETHERS FOR THE REMOVAL OF MERCAPTANS FROM HYDROCARBONS NALCO COMPANY 2012-01-19 US disclosed
WO-2012009390-A2 USE OF ALPHA-AMINO ETHERS FOR THE REMOVAL OF MERCAPTANS FROM HYDROCARBONS NALCO COMPANY (US) 2012-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130126429-A1 AMINE SULFIDE SCAVENGERS, METHODS OF USING, AND METHODS OF MAKING SRM, SMOX, BHMT2 HRH3 1922/4885MEN1 3669/4885KMT2A 135/4885
US-20130131387-A1 METHODS AND COMPOUNDS FOR IMPROVING SULFIDE SCAVENGING ACTIVITY SRM, SMOX, MGMT HRH3 3572/4885MEN1 4562/4885KMT2A 259/4885
US-20130172623-A1 SULFIDE SCAVENGERS, METHODS FOR MAKING AND METHODS FOR USING CBS, TST, GSS HRH3 3733/4885MEN1 3709/4885KMT2A 3923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.