SCHEMBL346736

SCHEMBL346736

CC(=O)c1c(C)c(C)nc2c(F)cc(C(C)(C)C)cc12

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.36
PTGFR P43088 1/20 0.33
PDE10A Q9Y233 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
TP53 P04637 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29979517 1.00 DHODH (0.36) DHODHPTGFRPDE10ASMN1; SMN2KMT2A
Acetic Acid SCHEMBL28595977 0.89 DHODH (0.44) DHODHPTGFRPDE10AALDH1A1HTT
SCHEMBL6856342 0.85 DHODH (0.38) DHODHPTGFRSMN1; SMN2KMT2AKDM4E
SCHEMBL6858360 0.85 DHODH (0.34) DHODHPTGFRPDE10AKMT2AMEN1
SCHEMBL6855230 0.84 FASN (0.34) DHODHPTGFRALDH1A1
SCHEMBL6858350 0.83 ALDH1A1 (0.40) DHODHSMN1; SMN2KMT2AKDM4EMEN1
SCHEMBL6857752 0.82 DHODH (0.31) DHODH
SCHEMBL6855568 0.82 DHODH (0.32) DHODHPTGFRALDH1A1HSD17B10
SCHEMBL6858344 0.81 HTR7 (0.34) DHODHPDE10ASMN1; SMN2KMT2AMEN1
SCHEMBL6851310 0.80 ADORA3 (0.39) KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115606598-A Fungicidal composition and method for controlling harmful fungi 石原产业株式会社 2023-01-17 CN claimed
CN-113598173-A Fungicidal composition and method for controlling harmful fungi 石原产业株式会社 2021-11-05 CN claimed
CN-109673644-A The method of Fungicidal composition and prevention and treatment harmful fungoid 石原产业株式会社 2019-04-26 CN claimed
EP-2205096-B1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI ISHIHARA SANGYO KAISHA (JP) 2017-04-12 EP claimed
US-8568755-B2 Fungicidal composition and method for controlling noxious fungi ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-10-29 US claimed
US-20100255116-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-10-07 US claimed
EP-2205096-A2 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-07-14 EP claimed
WO-2009060734-A2 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-05-14 WO claimed
US-6787557-B2 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia MEIJI SEIKA KAISHA, LTD. (JP) 2004-09-07 US claimed
CN-115606598-A Fungicidal composition and method for controlling harmful fungi 石原产业株式会社 2023-01-17 CN disclosed
CN-113598173-B Fungicidal composition and method for controlling harmful fungi 石原产业株式会社 2022-11-04 CN disclosed
CN-113598173-A Fungicidal composition and method for controlling harmful fungi 石原产业株式会社 2021-11-05 CN disclosed
CN-109673644-B Fungicidal composition and method for controlling harmful fungi 石原产业株式会社 2021-08-27 CN disclosed
US-9848601-B2 Pesticidal composition, and method for controlling pests ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-12-26 US disclosed
WO-2010021404-A2 METHOD FOR CONTROLLING DEGRADATION OF AGRICULTURAL CHEMICAL ACTIVE INGREDIENT ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-02-25 WO disclosed
WO-2009088103-A1 PYRIDYLAMIDINE COMPOUND OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL FUNGICIDE COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-07-16 WO disclosed
WO-2009060734-A2 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-05-14 WO disclosed
US-6787557-B2 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia MEIJI SEIKA KAISHA, LTD. (JP) 2004-09-07 US disclosed
US-20030176459-A1 Rice blast control agents MEIJI SEIKA PHARMA CO., LTD. (JP) 2003-09-18 US disclosed
EP-1291344-A1 RICE BLAST CONTROL AGENTS MEIJI SEIKA KAISHA LTD. (JP) 2003-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176459-A1 Rice blast control agents CNOT1, OSR1, RER1 DHODH 3180/4885PTGFR 4795/4885PDE10A 3358/4885
US-20100255116-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING NOXIOUS FUNGI DPM1, ETF1, GABBR1 DHODH 1552/4885PTGFR 4565/4885PDE10A 3817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.