Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858350 | 0.87 | ALDH1A1 (0.40) | DHODHKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL346736 | 0.85 | DHODH (0.36) | DHODHKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL29979517 | 0.85 | DHODH (0.36) | DHODHKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6851310 | 0.84 | ADORA3 (0.39) | ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL6855568 | 0.84 | DHODH (0.32) | DHODHALDH1A1PTGFR | |
| Acetic Acid SCHEMBL28595977 | 0.83 | DHODH (0.44) | DHODHALDH1A1PTGFRHTT | |
| SCHEMBL6857733 | 0.82 | ESR1 (0.40) | ALDH1A1HPGDKDM4EATMSMN1; SMN2 | |
| SCHEMBL6858360 | 0.82 | DHODH (0.34) | DHODHKMT2AMEN1PTGFRCYP3A4 | |
| SCHEMBL6855230 | 0.81 | FASN (0.34) | DHODHALDH1A1PTGFR | |
| SCHEMBL6857752 | 0.79 | DHODH (0.31) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787557-B2 | 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-09-07 | — | — | US | claimed |
| US-6787557-B2 | 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| US-20030176459-A1 | Rice blast control agents | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1291344-A1 | RICE BLAST CONTROL AGENTS | MEIJI SEIKA KAISHA LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176459-A1 | Rice blast control agents | CNOT1, OSR1, RER1 | DHODH 3180/4885KMT2A 2858/4885ALDH1A1 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.