SCHEMBL6857752

SCHEMBL6857752

CC(=O)OCC(=O)c1c(C)c(C)nc2c(F)cc(C(C)(C)C)cc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6855568 0.88 DHODH (0.32) DHODH
SCHEMBL6858360 0.84 DHODH (0.34) DHODH
SCHEMBL6855230 0.83 FASN (0.34) DHODH
SCHEMBL346736 0.82 DHODH (0.36) DHODH
SCHEMBL29979517 0.82 DHODH (0.36) DHODH
SCHEMBL6858350 0.82 ALDH1A1 (0.40) DHODH
Acetic Acid SCHEMBL28595977 0.80 DHODH (0.44) DHODH
SCHEMBL6858344 0.80 HTR7 (0.34) DHODH
SCHEMBL6856342 0.79 DHODH (0.38) DHODH
SCHEMBL6851310 0.79 ADORA3 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787557-B2 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia MEIJI SEIKA KAISHA, LTD. (JP) 2004-09-07 US claimed
US-6787557-B2 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia MEIJI SEIKA KAISHA, LTD. (JP) 2004-09-07 US disclosed
US-20030176459-A1 Rice blast control agents MEIJI SEIKA PHARMA CO., LTD. (JP) 2003-09-18 US disclosed
EP-1291344-A1 RICE BLAST CONTROL AGENTS MEIJI SEIKA KAISHA LTD. (JP) 2003-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176459-A1 Rice blast control agents CNOT1, OSR1, RER1 DHODH 3180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.