SCHEMBL6855230

SCHEMBL6855230

CCCC(=O)c1c(C)c(C)nc2c(F)cc(C(C)(C)C)cc12

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FASN P49327 2/20 0.34
DHODH Q02127 1/20 0.33
PTGFR P43088 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6858344 0.94 HTR7 (0.34) DHODHALDH1A1LMNA
SCHEMBL6858360 0.91 DHODH (0.34) DHODHPTGFR
SCHEMBL6855568 0.85 DHODH (0.32) DHODHPTGFRALDH1A1
SCHEMBL29979517 0.84 DHODH (0.36) DHODHPTGFRALDH1A1
SCHEMBL346736 0.84 DHODH (0.36) DHODHPTGFRALDH1A1
SCHEMBL6858350 0.84 ALDH1A1 (0.40) DHODHALDH1A1LMNA
SCHEMBL6851310 0.83 ADORA3 (0.39) ALDH1A1
SCHEMBL6857752 0.83 DHODH (0.31) DHODH
Acetic Acid SCHEMBL28595977 0.82 DHODH (0.44) DHODHPTGFRALDH1A1
SCHEMBL6857733 0.81 ESR1 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787557-B2 2,3-dimethyl-6-t-butyl-8-fluoro-4-hydroxyquinoline or ester derivatives; plant fungicides; Pyricularia MEIJI SEIKA KAISHA, LTD. (JP) 2004-09-07 US disclosed
US-20030176459-A1 Rice blast control agents MEIJI SEIKA PHARMA CO., LTD. (JP) 2003-09-18 US disclosed
EP-1291344-A1 RICE BLAST CONTROL AGENTS MEIJI SEIKA KAISHA LTD. (JP) 2003-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176459-A1 Rice blast control agents CNOT1, OSR1, RER1 FASN 3733/4885DHODH 3180/4885PTGFR 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.