Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647824 | 0.92 | TSHR (0.31) | TSHR | |
| SCHEMBL10759055 | 0.88 | TSHR (0.32) | TSHR | |
| SCHEMBL346876 | 0.88 | TSHR (0.32) | TSHR | |
| SCHEMBL304318 | 0.88 | CEL (0.33) | TSHR | |
| SCHEMBL561422 | 0.88 | TSHR (0.32) | TSHR | |
| SCHEMBL6238652 | 0.86 | KMT2A (0.36) | — | |
| SCHEMBL15751193 | 0.82 | ESR2 (0.36) | TSHRLMNASMN1; SMN2TP53 | |
| SCHEMBL15751190 | 0.82 | ESR2 (0.36) | TSHRLMNASMN1; SMN2TP53 | |
| SCHEMBL18022413 | 0.73 | — | — | |
| SCHEMBL10679447 | 0.71 | KMT2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589666-A | Polyester polyol and preparation method and application thereof | 杭州之江有机硅化工有限公司 | 2023-08-15 | — | — | CN | claimed |
| US-12534606-B2 | Functionalized propylene based elastomer composition and method of making | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2026-01-27 | — | — | US | disclosed |
| US-20250179054-A1 | THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF | TERNS PHARMACEUTICALS, INC. | 2025-06-05 | — | — | US | disclosed |
| EP-3277752-B1 | PROPYLENE-BASED POLYMER COMPOSITIONS FOR GRIP APPLICATIONS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-09-18 | — | — | EP | disclosed |
| EP-3752538-B1 | METALLOCENE CATALYST FEED SYSTEM FOR SOLUTION POLYMERIZATION PROCESS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-07-03 | — | — | EP | disclosed |
| EP-4077536-B1 | FUNCTIONALIZED PROPYLENE BASED ELASTOMER COMPOSITION AND METHOD OF MAKING | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-01-31 | — | — | EP | disclosed |
| US-20240011198-A1 | Nonwoven Fabrics with Improved Haptics and Mechanical Properties | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-01-11 | — | — | US | disclosed |
| US-20230357454-A1 | Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-11-09 | — | — | US | disclosed |
| US-11780981-B2 | Foam beads and method of making the same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-10-10 | — | — | US | disclosed |
| EP-4248004-A1 | NONWOVEN FABRICS WITH IMPROVED HAPTICS AND MECHANICAL PROPERTIES | ExxonMobil Chemical Patents Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| US-6465462-B1 | COGNITION ENHANCEMENT FOR DEMENTING ILLNESSES SUCH AS ALZHEIMER'S DISEASE | MERCK SHARP & DOHME LTD. | 2002-10-15 | — | — | US | disclosed |
| US-6255305-B1 | PSYCHOLOGICAL DISORDERS | MERCK SHARP & DOHME LIMITED (GB) | 2001-07-03 | — | — | US | disclosed |
| EP-0915877-A1 | SUBSTITUTED TRIAZOLO PYRIDAZINE DERIVATIVES AS INVERSE AGONISTS OF THE GABA A?$g(a)5 RECEPTOR SUBTYPE | MERCK SHARP & DOHME LTD. (GB) | 1999-05-19 | — | — | EP | disclosed |
| EP-0915875-A2 | SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004560-A1 | SUBSTITUTED TRIAZOLO PYRIDAZINE DERIVATIVES AS INVERSE AGONISTS OF THE GABAAα5 RECEPTOR SUBTYPE | MERCK SHARP & DOHME LIMITED (GB) | 1998-02-05 | — | — | WO | disclosed |
| WO-1998004559-A2 | SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 1998-02-05 | — | — | WO | disclosed |
| EP-0138748-B1 | FLUOROALIPHATIC -THIO, -SULFINYL OR -SULFONYL SUBSTITUTED BICYCLOALIPHATIC AMIC ACID AMINE SALTS AND COMPOSITIONS AND USE THEREOF | CIBA-GEIGY AG (CH) | 1987-01-21 | — | — | EP | disclosed |
| US-4590129-A | OIL AND WATER REPELLENT FOR CELLULOSE AND POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1986-05-20 | — | — | US | disclosed |
| US-4515640-A | RENDERING CELLULOSE AND POLYAMIDES OIL AND WATER REPELLENT | CIBA GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0138748-A1 | Fluoroaliphatic -thio, -sulfinyl or -sulfonyl substituted bicycloaliphatic amic acid amine salts and compositions and use thereof | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179054-A1 | THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF | THRB, THRA, TRHR | TSHR 4/4885TDP1 3432/4885KDM4E 3160/4885 |
| US-12534606-B2 | Functionalized propylene based elastomer composition and method of making | F8, CCT8, MSTN | TSHR 769/4885TDP1 3597/4885KDM4E 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.