Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668448 | 0.98 | NPC1 (0.49) | NPC1ELANEMAPTRAB9ACNR2 | |
| SCHEMBL9499089 | 0.83 | NPC1 (0.52) | NPC1MAPTRAB9ACNR2PSMB8 | |
| SCHEMBL28441097 | 0.82 | NPC1 (0.54) | NPC1MAPTRAB9ACNR2SMN1; SMN2 | |
| SCHEMBL14542334 | 0.82 | LTA4H (0.54) | NPC1MAPTRAB9ACNR2SMN1; SMN2 | |
| SCHEMBL29818603 | 0.82 | NPC1 (0.54) | NPC1MAPTRAB9ACNR2SMN1; SMN2 | |
| SCHEMBL12411071 | 0.80 | MAPT (0.46) | NPC1MAPTRAB9ACNR2PSMB8 | |
| SCHEMBL2123636 | 0.79 | NPC1 (0.48) | NPC1MAPTRAB9ACNR2PSMB8 | |
| SCHEMBL20733702 | 0.79 | PSMB8 (0.50) | NPC1MAPTRAB9ACNR2PSMB8 | |
| SCHEMBL28848909 | 0.79 | NPC1 (0.48) | NPC1MAPTRAB9APSMB8SMN1; SMN2 | |
| SCHEMBL9165943 | 0.79 | ELANE (0.61) | NPC1ELANEMAPTRAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113439084-B | Sesqui-carcinomycin analogue | 奥克兰联合服务有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20240335442-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO – UFRJ (BR) | 2024-10-10 | — | — | US | disclosed |
| US-20240217950-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-04 | — | — | US | disclosed |
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| CN-117069725-A | Imidazopyridazine substituted benzene ring derivative, preparation method, pharmaceutical composition and application | 上海赛默罗生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| US-20230117695-A1 | ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-04-20 | — | — | US | disclosed |
| US-11492352-B2 | Arenavirus growth inhibitor comprising polycyclic carbamoylpyridone derivative | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2022-11-08 | — | — | US | disclosed |
| US-20220098215-A1 | DUOCARMYCIN ANALOGUES | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-03-31 | — | — | US | disclosed |
| US-20210292321-A1 | ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2021-09-23 | — | — | US | disclosed |
| US-20210228550-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2021-07-29 | — | — | US | disclosed |
| WO-2002016327-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS NEUTROPHIL INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |
| US-5391475-A | Selenium sensitizer; green light sensitive silver halide emulsion layer; increased sensitivity in green short wavelength region; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5061618-A | Containing cyanide and azine dyes | EASTMAN KODAK COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-5015561-A | Method for forming a direct positive image | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-14 | — | — | US | disclosed |
| EP-0385496-A2 | Color light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |
| EP-0368327-A2 | Light-sensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |
| EP-0357082-A2 | Silver halide photographic emulsions | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| EP-0331185-A2 | Silver halide photographic element for forming direct positive images and a method for forming said images | FUJI PHOTO FILM CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0306019-A2 | Silver halide photographic material and method for forming an image | FUJI PHOTO FILM CO., LTD. (JP) | 1989-03-08 | — | — | EP | disclosed |
| US-3953216-A | BENZOXAZOLES, NAPHTHOXAZOLES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492352-B2 | Arenavirus growth inhibitor comprising polycyclic carbamoylpyridone derivative | LUC7L2, CXCR6, RRP12 | NPC1 1486/4885ELANE 1795/4885MAPT 4801/4885 |
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | NPC1 3250/4885ELANE 805/4885MAPT 4568/4885 |
| US-20240335442-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | SCN1A, SCN7A, SCN8A | NPC1 756/4885ELANE 1311/4885MAPT 3908/4885 |
| US-20240217950-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | DDT, ACHE, PNMT | NPC1 2339/4885ELANE 3597/4885MAPT 225/4885 |
| US-20230117695-A1 | ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | CDK7, CCNA1, CCR10 | NPC1 2071/4885ELANE 2021/4885MAPT 4836/4885 |
| US-20220098215-A1 | DUOCARMYCIN ANALOGUES | TOP2A, TOP2B, MUS81 | NPC1 3762/4885ELANE 3978/4885MAPT 1921/4885 |
| US-20210228550-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | NPC1 1750/4885ELANE 158/4885MAPT 2052/4885 |
| US-20210292321-A1 | ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | CCNA1, CDK7, CCR10 | NPC1 2018/4885ELANE 1987/4885MAPT 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.