Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981986 | 0.84 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1POLBKIF11KDM4E | |
| SCHEMBL16461464 | 0.82 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1POLBKDM4E | |
| SCHEMBL7996334 | 0.82 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL27963643 | 0.81 | FOS (0.30) | — | |
| SCHEMBL6225863 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL6225865 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL25223884 | 0.77 | VNN1 (0.32) | — | |
| SCHEMBL1120452 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL25402026 | 0.76 | TRPV3 (0.30) | — | |
| SCHEMBL7439427 | 0.76 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1KDM4EKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509439-B2 | Anti-malarial agents | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2025-12-30 | — | — | US | disclosed |
| US-12497399-B2 | Fluorinated integrin antagonists | OCUTERRA THERAPEUTICS, INC. (US) | 2025-12-16 | — | — | US | disclosed |
| US-20250368625-A1 | PIPERAZINES | Grünenthal GmbH (DE) | 2025-12-04 | — | — | US | disclosed |
| US-12297197-B2 | Pyrazolopyridine compound as RET inhibitor and application thereof | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) | 2025-05-13 | — | — | US | disclosed |
| US-12286432-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | OCUTERRA THERAPEUTICS, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| CN-115380027-B | Novel antimalarial agents | 肯塔基大学研究基金会 | 2024-10-18 | — | — | CN | disclosed |
| WO-2024175026-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICAL USE THEREOF | 哈尔滨三联药业股份有限公司 | 2024-08-29 | — | — | WO | disclosed |
| CN-118546109-A | Nitrogen-containing heterocyclic compound and medical application thereof | 哈尔滨三联药业股份有限公司 | 2024-08-27 | — | — | CN | disclosed |
| US-20240246932-A1 | ARYL 3-OXOPIPERAZINE CARBOXAMIDES AND HETEROARYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
| US-20240140942-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2024-05-02 | — | — | US | disclosed |
| US-5750704-A | INSECTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5580889-A | Insecticidal nitromethyl or niteoimino-heteromethyl-heterocyclics | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-03 | — | — | US | disclosed |
| US-5461167-A | 2-chloro-5-chloromethyl thiazole; insecticide | NIHON BAYER AGROCHEM K.K. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5428032-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5298507-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5204360-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297197-B2 | Pyrazolopyridine compound as RET inhibitor and application thereof | RET, BRAF, RAF1 | ALDH1A1 1309/4885L3MBTL1 4742/4885POLB 3427/4885 |
| US-20240140942-A1 | FLUORINATED INTEGRIN ANTAGONISTS | ITGB5, ITGB1, ITGA5 | ALDH1A1 2260/4885L3MBTL1 4764/4885POLB 4045/4885 |
| US-20240246932-A1 | ARYL 3-OXOPIPERAZINE CARBOXAMIDES AND HETEROARYL 3-OXOPIPERAZINE CARBOXAMIDES AS NAV1.8 INHIBITORS | TRPV1, SCN8A, SCN2A | ALDH1A1 2844/4885L3MBTL1 4098/4885POLB 4835/4885 |
| US-12509439-B2 | Anti-malarial agents | RCC1, PFN1, NHERF1 | ALDH1A1 1353/4885L3MBTL1 3793/4885POLB 3838/4885 |
| US-12286432-B2 | Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof | FFAR3, FFAR2, FFAR1 | ALDH1A1 1949/4885L3MBTL1 4681/4885POLB 4210/4885 |
| US-12497399-B2 | Fluorinated integrin antagonists | ITGB5, ITGB1, ITGA5 | ALDH1A1 2260/4885L3MBTL1 4764/4885POLB 4045/4885 |
| US-20250368625-A1 | PIPERAZINES | SSTR4, SSTR5, SSTR2 | ALDH1A1 2067/4885L3MBTL1 4881/4885POLB 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.