Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | F13A1 | P00488 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | TGM1 | P22735 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22829637 | 1.00 | DPP4 (0.61) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL3489847 | 0.96 | CTSL (0.62) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL22469041 | 0.92 | HSD11B1 (0.62) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL3667335 | 0.91 | CTSL (0.68) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL13740409 | 0.91 | CTSL (0.68) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL3003867 | 0.91 | CTSL (0.68) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL25203367 | 0.87 | HSD11B1 (0.60) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL2551898 | 0.86 | DPP4 (0.62) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL22469698 | 0.86 | DPP4 (0.54) | DPP4DPP7KCNH2CTSLCTSB | |
| SCHEMBL18956862 | 0.86 | CTSL (0.58) | DPP4DPP7KCNH2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-110194770-B | Peptidyl arginine deiminase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3760628-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-20200407370-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | NANJING TRANSTHERA BIOSCIENCES CO., LTD. (CN) | 2020-12-31 | — | — | US | disclosed |
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407370-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | PADI4, PADI2, PADI1 | DPP4 49/4885DPP7 299/4885KCNH2 4037/4885 |
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | DPP4 583/4885DPP7 872/4885KCNH2 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.