SCHEMBL349725

SCHEMBL349725

CC(C)(N)Cc1ccc(F)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.61
HTR2A P28223 1/20 0.61
SLC6A4 P31645 1/20 0.61
HRH1 P35367 1/20 0.61
HTR2B P41595 1/20 0.61
CHRNA4 P43681 1/20 0.61
SLC6A3 Q01959 1/20 0.61
TAAR1 Q96RJ0 4/20 0.60
LOXL2 Q9Y4K0 1/20 0.48
IDO1 P14902 3/20 0.43
AGXT P21549 2/20 0.43
AOC3 Q16853 1/20 0.42
MAOB P27338 3/20 0.39
HPGD P15428 1/20 0.39
LMNA P02545 1/20 0.39
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2799159 0.98 SLC6A2 (0.59) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL22462571 0.90 SLC6A2 (0.52) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL25343157 0.86 LOXL2 (0.48) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL25343692 0.81 SLC6A2 (0.42) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL25342534 0.81 SLC6A2 (0.61) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL15812042 0.80 LOXL2 (0.48) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL7267223 0.80 LOXL2 (0.43) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL228926 0.80 SLC6A2 (0.67) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL2615503 0.80 ESR1 (0.58) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL72988 0.80 ESR1 (0.58) SLC6A2HTR2ASLC6A4HRH1HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101704756-B The synthetic method of 1-(4-fluorophenyl)-2-methyl-2-propylamine 大连九信精细化工有限公司 2017-12-05 CN claimed
US-8431565-B2 Substituted imidazoheterocycles CARA THERAPEUTICS, INC. (US) 2013-04-30 US claimed
CN-101704756-A Synthesis method of 1- (4-fluorophenyl) -2-methyl-2-propylamine DALIAN KAIFEI FINE CHEMICALS C 2010-05-12 CN claimed
US-20090149450-A1 SUBSTITUTED IMIDAZOHETEROCYCLES CARA THERAPEUTICS, INC. (US) 2009-06-11 US claimed
EP-1144384-B1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARM INC (US) 2007-10-31 EP claimed
US-7009052-B2 Sulfonamide derivatives WARNER LAMBERT COMPANY LLC (US) 2006-03-07 US claimed
US-20050004367-A1 Sulfonamide derivatives DU DANIEL Y (US) 2005-01-06 US claimed
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC 2004-12-23 US claimed
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed
US-20250049036-A1 SUBSTITUTED FUSED BICYCLIC PYRIDINE CARBOXAMIDE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2025-02-13 US disclosed
EP-4448494-A1 NOVEL SUBSTITUTED FUSED BICYCLIC PYRIDINE CARBOXAMIDE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI PI Industries Ltd. (IN) 2024-10-23 EP disclosed
US-12059422-B2 (Alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases MEI PHARMA, INC. (US) 2024-08-13 US disclosed
EP-3715342-B1 FLUOROSULFONYL-CONTAINING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF ZHONGHONGXIN INVEST HOLDINGS SHENZHEN CO LTD (CN) 2024-08-07 EP disclosed
US-20240083839-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-03-14 US disclosed
US-5621010-A ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS NISSHIN FLOUR MILLING CO., LTD. (JP) 1997-04-15 US disclosed
US-5514502-A STYRENE-MALEIC ANHYDRIDE MODIFIED WITH AMINE FUJI PHOTO FILM CO., LTD. (JP) 1996-05-07 US disclosed
EP-0625507-A2 Urea derivatives and their use as acat inhibitors NISSHIN FLOUR MILLING CO., LTD. (JP) 1994-11-23 EP disclosed
US-5153327-A 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease E. R. SQUIBB & SONS, INC. (US) 1992-10-06 US disclosed
US-5100889-A Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor E. R. SQUIBB & SONS, INC. (US) 1992-03-31 US disclosed
US-3979514-A Process for interrupting pregnancy with sulfonamidoaminophene interceptive agents MEAD JOHNSON & COMPANY (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049036-A1 SUBSTITUTED FUSED BICYCLIC PYRIDINE CARBOXAMIDE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CBR3, C5, CBR1 SLC6A2 4827/4885HTR2A 3575/4885SLC6A4 4768/4885
US-20040259887-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 SLC6A2 1393/4885HTR2A 138/4885SLC6A4 1093/4885
US-12059422-B2 (Alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases CCNI, CCNK, CCNA1 SLC6A2 4508/4885HTR2A 1861/4885SLC6A4 4601/4885
US-20050004367-A1 Sulfonamide derivatives AR, SULT2A1, SHBG SLC6A2 584/4885HTR2A 130/4885SLC6A4 241/4885
US-20090149450-A1 SUBSTITUTED IMIDAZOHETEROCYCLES CNR1, CNR2, TRPV1 SLC6A2 2121/4885HTR2A 550/4885SLC6A4 2157/4885
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 SLC6A2 2245/4885HTR2A 253/4885SLC6A4 2051/4885
US-20240083839-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES AND DISORDERS PRMT8, SIRT1, PRMT3 SLC6A2 3591/4885HTR2A 2772/4885SLC6A4 4235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.