Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832034 | 0.86 | CASP1 (0.56) | CASP1CASP3 | |
| SCHEMBL5181237 | 0.80 | KYNU (0.60) | CASP1 | |
| SCHEMBL7736831 | 0.80 | KYNU (0.60) | CASP1 | |
| SCHEMBL20756235 | 0.79 | CTSL (0.54) | CASP1CASP3 | |
| SCHEMBL19275168 | 0.79 | CTSL (0.54) | CASP1CASP3 | |
| SCHEMBL7364542 | 0.79 | CASP3 (0.53) | CASP1CASP3 | |
| SCHEMBL20756965 | 0.79 | CASP1 (0.49) | CASP1CASP3 | |
| SCHEMBL3686640 | 0.78 | CASP1 (0.74) | CASP1CASP3 | |
| SCHEMBL29802628 | 0.78 | CASP1 (0.74) | CASP1CASP3 | |
| SCHEMBL7742845 | 0.78 | PSMB1 (0.56) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158924-A1 | Expression of the cysteine protease legumain in vascular and inflammatory diseases | WYETH, LLC (US) | 2010-06-24 | — | — | US | disclosed |
| US-20070274987-A1 | Expression of the cysteine protease legumain in vascular and inflammatory diseases | WYETH | 2007-11-29 | — | — | US | disclosed |