Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicotinuric Acid SCHEMBL30183567 | 1.00 | THRB (0.75) | THRBMEN1KMT2ANPC1RAB9A | |
| Nicotinuric Acid SCHEMBL9227412 | 0.98 | THRB (0.73) | THRBMEN1KMT2ANPC1RAB9A | |
| Nicotinuric Acid SCHEMBL28292410 | 0.98 | THRB (0.73) | THRBMEN1KMT2ANPC1RAB9A | |
| Nicotinuric Acid SCHEMBL28292397 | 0.98 | THRB (0.73) | THRBMEN1KMT2ANPC1RAB9A | |
| Nicotinuric Acid SCHEMBL1219783 | 0.92 | THRB (0.65) | THRBMEN1KMT2ANPC1RAB9A | |
| Nicotinuric Acid SCHEMBL15012491 | 0.91 | THRB (0.63) | THRBMEN1KMT2ANPC1RAB9A | |
| Nicotinuric Acid SCHEMBL1219715 | 0.91 | THRB (0.63) | THRBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22983350 | 0.89 | NAMPT (0.66) | THRBMEN1KMT2ANPC1RAB9A | |
| Nicotinuric Acid SCHEMBL1219821 | 0.87 | THRB (0.58) | THRBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3864600 | 0.86 | THRB (0.75) | THRBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 975 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4687829-A1 | COMPOSITION FOR CARING FOR KERATIN MATERIALS | L'OREAL (FR) | 2026-02-11 | — | — | EP | claimed |
| US-20250381116-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | claimed |
| CN-120044159-A | Polygonatum sibiricum medicinal material species identification method based on polygonatum sibiricum characteristic compound and application | 河北北方学院 | 2025-05-27 | — | — | CN | claimed |
| US-20250161201-A1 | COSMETIC COMPOSITION | THE BOOTS COMPANY PLC (GB) | 2025-05-22 | — | — | US | claimed |
| EP-4543408-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | L'OREAL (FR) | 2025-04-30 | — | — | EP | claimed |
| EP-4479146-A1 | COSMETIC COMPOSITION | The Boots Company PLC (GB) | 2024-12-25 | — | — | EP | claimed |
| CN-119110720-A | Cosmetic composition | 布茨公司 | 2024-12-10 | — | — | CN | claimed |
| WO-2024197798-A1 | COMPOSITION FOR CARING FOR KERATIN MATERIALS | L'OREAL (FR) | 2024-10-03 | — | — | WO | claimed |
| WO-2023248248-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | L'ORÉAL (FR) | 2023-12-28 | — | — | WO | claimed |
| WO-2023156070-A1 | COSMETIC COMPOSITION | THE BOOTS COMPANY PLC (GB) | 2023-08-24 | — | — | WO | claimed |
| WO-2007053773-A1 | COMPOSITIONS AND METHODS USING NICOTINIC ACID FOR TREATMENT OF HYPERCHOLESTEROLEMIA, HYPERLIPIDEMIA AND CARDIOVASCULAR DISEASE | HENDRIX CURT (US) | 2007-05-10 | — | — | WO | claimed |
| EP-1633334-B1 | TOPICAL ADMINISTRATION OF VASOACTIVE VITAMIN B3 COMPOUNDS FOR PROMOTING SLEEP | PROCTER & GAMBLE (US) | 2006-11-15 | — | — | EP | claimed |
| EP-1633334-A2 | A METHOD OF PROMOTING SLEEP USING TOPICAL ADMINISTRATION OF VASOACTIVE AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-15 | — | — | EP | claimed |
| WO-2005002554-A2 | A METHOD OF PROMOTING SLEEP USING TOPICAL ADMINISTRATION OF VASOACTIVE AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-13 | — | — | WO | claimed |
| US-20040254202-A1 | Method of promoting sleep using topical administration of vasoactive agents | THE PROCTER & GAMBLE COMPANY | 2004-12-16 | — | — | US | claimed |
| US-6818229-B1 | ONCE A DAY DOSAGE WITHOUT CAUSING DRUG INDUCED HEPATIC TOXICITY; FDA ORANGE BOOK LISTED PATENT FOR NIACIN AND SIMVASTATIN | KOS PHARMACEUTICALS, INC. | 2004-11-16 | — | — | US | claimed |
| US-20040097482-A1 | Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications | SCHERING CORPORATION | 2004-05-20 | — | — | US | claimed |
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | L'OREAL (FR) | 2002-12-26 | — | — | US | claimed |
| US-6143770-A | MIXTURES OF TOCOTRIENOL AND NICOTINIC ACID | LIPOGENICS, INC. (US) | 2000-11-07 | — | — | US | claimed |
| US-5430049-A | Treating hyperproliferative disorders | GAUT ZANE N (US) | 1995-07-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | CYP24A1, CYP27B1, CYP2R1 | THRB 2820/4885MEN1 4140/4885KMT2A 4139/4885 |
| US-20250161201-A1 | COSMETIC COMPOSITION | CYP19A1, SHBG, HSD17B11 | THRB 3106/4885MEN1 2548/4885KMT2A 3132/4885 |
| US-20250381116-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TBCB, CCNB3, CYP24A1 | THRB 494/4885MEN1 1459/4885KMT2A 3398/4885 |
| US-20040097482-A1 | Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications | CYP46A1, GPR119, APOB | THRB 671/4885MEN1 325/4885KMT2A 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.