Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EBP | Q15125 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38790 | 0.95 | POLB (0.54) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL15513356 | 0.93 | POLB (0.53) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Ethylene SCHEMBL25203709 | 0.92 | POLB (0.51) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28899516 | 0.87 | POLB (0.51) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3283894 | 0.84 | NPC1 (0.57) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3068904 | 0.82 | GAA (0.44) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6212986 | 0.81 | POLB (0.70) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1743272 | 0.81 | MAPT (0.48) | POLBNPC1RAB9ATSHRKMT2A | |
| SCHEMBL29518429 | 0.81 | MAPT (0.48) | POLBNPC1RAB9ATSHRKMT2A | |
| SCHEMBL9453411 | 0.81 | SIGMAR1 (0.58) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580549-B2 | Esterases for separating plastics | HENKEL KGAA (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20100330013-A1 | AMADORIASES IN WASHING AND CLEANING PRODUCTS | HENKEL AG & CO. KGAA (DE) | 2010-12-30 | — | — | US | disclosed |
| US-20090275493-A1 | Novel Alkaline Protease from Bacillus Gibsonii and Washing and Cleaning Agents containing said Novel Alkaline Protease | HENKEL AG & CO. KGAA (DE) | 2009-11-05 | — | — | US | disclosed |
| US-20090258406-A1 | Use of esterases for separating plastics | HENKEL KGAA (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20090238889-A1 | Hyper-Branched Polymers for the Provision of Hygienic Characteristics | HENKEL AG & CO. KGAA (DE) | 2009-09-24 | — | — | US | disclosed |
| US-7510859-B2 | Subtilisin variants with improved perhydrolase activity | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2009-03-31 | — | — | US | disclosed |
| US-20070128129-A1 | ENZYMATIC BLEACHING SYSTEM | HENKEL AG & CO. KGAA (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20050282261-A1 | Novel choline oxidases | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | US | disclosed |
| US-20050281773-A1 | Subtilisin variants with improved perhydrolase activity | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | US | disclosed |
| US-20050205574-A1 | Water-soluble portion packaging with a filling | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-09-22 | — | — | US | disclosed |
| US-6569344-B1 | Fabrics; water soluble wetting agent and a salt | THE PROCTER & GAMBLE COMPANY | 2003-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050281773-A1 | Subtilisin variants with improved perhydrolase activity | DPEP1, HPN, DAO | SIGMAR1 3204/4885GRIN2D 4296/4885GRIN3B 2753/4885 |
| US-20090275493-A1 | Novel Alkaline Protease from Bacillus Gibsonii and Washing and Cleaning Agents containing said Novel Alkaline Protease | PRSS2, CPB2, GBA3 | SIGMAR1 4514/4885GRIN2D 3254/4885GRIN3B 3024/4885 |
| US-20070128129-A1 | ENZYMATIC BLEACHING SYSTEM | LPO, HAO2, APEH | SIGMAR1 1612/4885GRIN2D 3965/4885GRIN3B 3913/4885 |
| US-20100330013-A1 | AMADORIASES IN WASHING AND CLEANING PRODUCTS | ALPI, POLR1C, ZAP70 | SIGMAR1 4279/4885GRIN2D 4168/4885GRIN3B 3995/4885 |
| US-20090238889-A1 | Hyper-Branched Polymers for the Provision of Hygienic Characteristics | CD44, PCNA, ITGB3 | SIGMAR1 553/4885GRIN2D 1103/4885GRIN3B 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.