SCHEMBL352250

SCHEMBL352250

CCCc1cc2c(cc1CO)OCO2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.53
ALDH1A1 P00352 4/20 0.53
TSHR P16473 1/20 0.53
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2D6 P10635 4/20 0.44
CYP1A2 P05177 3/20 0.44
CYP2C19 P33261 3/20 0.44
CYP2C9 P11712 2/20 0.44
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HTT P42858 1/20 0.43
HPGD P15428 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALOX5 P09917 1/20 0.36
SCN1A P35498 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18633195 0.89 ALDH1A1 (0.50) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL9150800 0.88 CYP3A4 (0.53) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL30927115 0.83 CYP3A4 (0.56) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL28727085 0.83 KMT2A (0.41) CYP3A4ALDH1A1MEN1KMT2ACYP2D6
SCHEMBL9678088 0.83 CYP3A4 (0.56) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL6065166 0.82 CYP3A4 (0.71) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL9148130 0.80 CYP3A4 (0.53) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL1276072 0.80 CYP3A4 (0.49) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL30927087 0.78 CYP3A4 (0.73) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL128215 0.78 CYP3A4 (0.73) CYP3A4ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen CoLabs International Corporation (US) 2014-05-08 US claimed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 US claimed
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2005-08-25 US claimed
US-11957769-B2 Polyhydroxy fullerene sunscreen active agents and compositions THE CLEVELAND CLINIC FOUNDATION (US) 2024-04-16 US disclosed
EP-3411008-B1 COMPOSITIONS COMPRISING POLYHYDROXY FULLERENE SUNSCREEN ACTIVE AGENTS CLEVELAND CLINIC FOUND (US) 2023-05-17 EP disclosed
US-11166885-B2 Personal care gel and method COLGATE-PALMOLIVE COMPANY (US) 2021-11-09 US disclosed
EP-3506873-B1 PERSONAL CARE GEL AND METHOD COLGATE PALMOLIVE CO (US) 2021-11-03 EP disclosed
US-20210251860-A1 POLYHYDROXY FULLERENE SUNSCREEN ACTIVE AGENTS AND COMPOSITIONS CLEVELAND CLINIC FOUND (US) 2021-08-19 US disclosed
US-10925817-B2 Polyhydroxy fullerene sunscreen active agents and compositions THE CLEVELAND CLINIC FOUNDATION (US) 2021-02-23 US disclosed
US-10842728-B2 Light-absorbing compositions and methods of use ALLELE BIOTECHNOLOGY & PHARMACEUTICALS, INC. (US) 2020-11-24 US disclosed
EP-3672520-A1 LIGHT-ABSORBING COMPOSITIONS AND METHODS OF USE Allele Biotechnology And Pharmaceuticals, Inc. (US) 2020-07-01 EP disclosed
US-20070269526-A1 Carotenoid Composition and Method for Preparation Thereof BOS MICHAEL A 2007-11-22 US disclosed
US-7226582-B2 Sunscreen compositions and methods of use AQUEA SCIENTIFIC CORPORATION (US) 2007-06-05 US disclosed
US-20060210497-A1 Novel resorcinol derivatives UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2006-09-21 US disclosed
US-20060188458-A1 Sunscreen compositions and methods of use COLABS INTL CORP 2006-08-24 US disclosed
US-20060188462-A1 Skin care compositions containing a sugar amine BISSETT DONALD L 2006-08-24 US disclosed
US-20060182699-A1 Personal care compositions containing hydrophobically modified non-platelet particles PROCTER & GAMBLE COMPANY 2006-08-17 US disclosed
US-20050123575-A1 Spreadable compositions for topical use, an improved process of making same and methods of using same PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) 2005-06-09 US disclosed
US-5993787-A COMBINING WITH PROPYLENE CARBONATE AND GLYCEROL A SHORT CHAIN ALCOHOL OR GLYCOL IN AN AMOUNT SUFFICIENT TO EFFECTUATE MISCIBILITY BETWEEN SAID PROPYLENE CARBONATE AND SAID GLYCEROL. JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) 1999-11-30 US disclosed
US-5605894-A A MIXTURE OF SALICYLIC ACID, A SUNSCEEN, ANTIINFLAMMATORY AGENT, VITAMIN, ANTIOXIDANT, CHELATOR, RETINOID, A BENZUFURAN, AN N-ACETYL-L-CYSTEINE AND A SKIN PROTECTANT; NONTOXIC RICHARDSON-VICKS INC. (US) 1997-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 CYP3A4 1581/4885ALDH1A1 2904/4885TSHR 3321/4885
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen MSH6, TYR, CUTA CYP3A4 1425/4885ALDH1A1 854/4885TSHR 4315/4885
US-20060210497-A1 Novel resorcinol derivatives NR1H2, DEGS1, NR1H3 CYP3A4 489/4885ALDH1A1 1426/4885TSHR 2496/4885
US-20060188462-A1 Skin care compositions containing a sugar amine RBP4, RBP1, RARB CYP3A4 2189/4885ALDH1A1 1370/4885TSHR 747/4885
US-11166885-B2 Personal care gel and method CUTA, GLMN, ISG15 CYP3A4 4760/4885ALDH1A1 2002/4885TSHR 3463/4885
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 CYP3A4 1581/4885ALDH1A1 2904/4885TSHR 3321/4885
US-10842728-B2 Light-absorbing compositions and methods of use CYBA, BROX, S100A6 CYP3A4 4851/4885ALDH1A1 2131/4885TSHR 4644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.