Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL5830934 | 0.96 | CYP2A6 (0.50) | CYP2A6METAP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL415637 | 0.92 | CYP2A6 (0.54) | CYP2A6METAP1CYP1A2CYP3A4CYP2C9 | |
| Propene SCHEMBL8162420 | 0.89 | CYP2A6 (0.44) | CYP2A6METAP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6194916 | 0.88 | METAP1 (0.44) | CYP2A6METAP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10182282 | 0.87 | TDP1 (0.48) | CYP2A6METAP1TDP1L3MBTL1TDP2 | |
| SCHEMBL2591523 | 0.85 | METAP1 (0.52) | CYP2A6METAP1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL6195008 | 0.80 | METAP1 (0.44) | CYP2A6METAP1TDP1L3MBTL1TDP2 | |
| SCHEMBL13594 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL8701960 | 0.77 | PNMT (0.56) | METAP1CYP11B1CYP11B2TDP1L3MBTL1 | |
| SCHEMBL266510 | 0.75 | CYP2A6 (0.54) | CYP2A6CYP1A2CYP3A4CYP2C9CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 828 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678788-B | 1, 2-diaryl indole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-107619386-B | Aromatic ring [ c ] carbazole derivative and synthesis method thereof | 湘潭大学 | 2020-10-13 | — | — | CN | claimed |
| WO-2008100621-A2 | TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | claimed |
| US-6495023-B1 | METHODS USING NEUTRAL RED TO MEDIATE THE INTERCONVERSION OF CHEMICAL AND ELECTRICAL ENERGY. ELECTRICALLY REDUCED NEUTRAL RED HAS BEEN FOUND TO PROMOTE CELL GROWTH AND FORMATION OF REDUCED PRODUCTS BY REVERSIBLY INCREASING THE RATIO OF THE | MICHIGAN STATE UNIVERSITY | 2002-12-17 | — | — | US | claimed |
| CN-1314891-A | Synthesis of benzo (F) quinolinones | LILLY CO ELI (US) | 2001-09-26 | — | — | CN | claimed |
| EP-0969003-A2 | Process for the preparation of benzo[f]quinolinone derivatives and intermediates | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1999065878-A1 | SYNTHESIS OF BENZO[F]QUINOLINONES | ELI LILLY AND COMPANY (US) | 1999-12-23 | — | — | WO | claimed |
| EP-0701558-A1 | PROCESS OF MAKING SPIROCYCLES AND ANALOGS THEREOF | MERCK & CO. INC. (US) | 1996-03-20 | — | — | EP | claimed |
| US-5464762-A | Antiarrhythmia | MERCK & CO., INC. (US) | 1995-11-07 | — | — | US | claimed |
| WO-1994029317-A1 | PROCESS OF MAKING SPIROCYCLES AND ANALOGS THEREOF | MERCK & CO., INC. (US) | 1994-12-22 | — | — | WO | claimed |
| CN-122036628-A | Iron death inhibitor, preparation method and application thereof | 福建医科大学 | 2026-05-15 | — | — | CN | disclosed |
| US-12617777-B2 | GPR84 antagonists and uses thereof | Liminal Biosciences Limited (GB) | 2026-05-05 | — | — | US | disclosed |
| US-12570655-B2 | Cysteine covalent modifiers of AKT1 and uses thereof | TERREMOTO BIOSCIENCES, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| US-12543495-B2 | Composition, organic optoelectronic device and display device | SAMSUNG SDI CO., LTD. (KR) | 2026-02-03 | — | — | US | disclosed |
| WO-2025081045-A9 | CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| EP-0343830-A2 | Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes | ELI LILLY AND COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |
| US-4876340-A | Benzazecine derivatives for cognitive and memory functions | HOFFMANN-LA ROCHE INC. (US) | 1989-10-24 | — | — | US | disclosed |
| US-4749791-A | Benzo[f]quinoline intermediates | HOFFMANN-LA ROCHE INC. (US) | 1988-06-07 | — | — | US | disclosed |
| US-4732979-A | CEREBRAL INSUFFICIENCY | HOFFMANN-LA ROCHE INC. (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0230967-A2 | Benzazecine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1987-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617777-B2 | GPR84 antagonists and uses thereof | GPR84, GPR88, GPR3 | CYP2A6 2106/4885METAP1 4061/4885CYP1A2 1794/4885 |
| US-12570655-B2 | Cysteine covalent modifiers of AKT1 and uses thereof | AKT1, AKT2, AKT3 | CYP2A6 2153/4885METAP1 3086/4885CYP1A2 4074/4885 |
| US-12543495-B2 | Composition, organic optoelectronic device and display device | NR2E3, OXER1, ACVRL1 | CYP2A6 401/4885METAP1 3582/4885CYP1A2 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.