SCHEMBL355909

SCHEMBL355909

Cc1ccc(-n2c3ccc(B(O)O)cc3c3cc(B(O)O)ccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.50
LPL P06858 1/20 0.50
LIPG Q9Y5X9 1/20 0.50
POLB P06746 2/20 0.46
MAPT P10636 4/20 0.43
GAA P10253 3/20 0.43
KDM4E B2RXH2 2/20 0.43
ORAI1 Q96D31 1/20 0.41
ORAI2 Q96SN7 1/20 0.41
ORAI3 Q9BRQ5 1/20 0.41
TRPV6 Q9H1D0 1/20 0.41
HTT P42858 4/20 0.38
TP53 P04637 2/20 0.36
NOTUM Q6P988 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RAB9A P51151 1/20 0.35
GFER P55789 1/20 0.34
USP14 P54578 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30296694 0.92 KDM4E (0.44) CA2LPLLIPGPOLBMAPT
SCHEMBL355186 0.92 KDM4E (0.44) CA2LPLLIPGPOLBMAPT
SCHEMBL28718809 0.90 CA2 (0.50) CA2LPLLIPGPOLBMAPT
SCHEMBL29419985 0.90 CA2 (0.50) CA2LPLLIPGPOLBMAPT
SCHEMBL17885395 0.89 ENPP2 (0.38) CA2LPLLIPGPOLBKDM4E
SCHEMBL12362820 0.88 POLB (0.43) CA2LPLLIPGPOLBMAPT
SCHEMBL12362779 0.87 GAA (0.43) CA2LPLLIPGPOLBMAPT
SCHEMBL26218478 0.84 KDM4E (0.40) CA2LPLLIPGPOLBMAPT
SCHEMBL13431620 0.83 KDM4E (0.44) CA2LPLLIPGPOLBMAPT
SCHEMBL18525478 0.83 KDM4E (0.52) CA2POLBMAPTGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2477979-B1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORP (JP) 2016-10-26 EP disclosed
EP-2477979-B1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORP (JP) 2016-10-26 EP disclosed
US-8808879-B2 Phototherapy devices and methods comprising substituted carbazole compounds NITTO DENKO CORPORATION (JP) 2014-08-19 US disclosed
US-8808879-B2 Phototherapy devices and methods comprising substituted carbazole compounds NITTO DENKO CORPORATION (JP) 2014-08-19 US disclosed
US-8808879-B2 Phototherapy devices and methods comprising substituted carbazole compounds NITTO DENKO CORPORATION (JP) 2014-08-19 US disclosed
US-8586205-B2 Compounds for organic light emitting diode emissive layers NITTO DENKO CORPORATION (JP) 2013-11-19 US disclosed
US-8586205-B2 Compounds for organic light emitting diode emissive layers NITTO DENKO CORPORATION (JP) 2013-11-19 US disclosed
EP-2477979-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS Nitto Denko Corporation (JP) 2012-07-25 EP disclosed
WO-2012012295-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-26 WO disclosed
WO-2012012295-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-26 WO disclosed
US-20120016449-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
US-20120016449-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
US-20120016449-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
WO-2011034967-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-24 WO disclosed
WO-2011034967-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-24 WO disclosed
US-20110062386-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed
US-20110062386-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed
US-20110062386-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS NITTO DENKO CORPORATION (JP) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016449-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING SUBSTITUTED CARBAZOLE COMPOUNDS TYR, PPOX, CRY1 CA2 1747/4885LPL 3646/4885LIPG 2845/4885
US-20110062386-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE EMISSIVE LAYERS ALOX12, ALOX15B, ALOX15 CA2 4381/4885LPL 475/4885LIPG 1471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.