SCHEMBL357107

SCHEMBL357107

CCC(Cl)C(=O)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
FFAR3 O14843 2/20 0.36
CYP2C9 P11712 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
MME P08473 1/20 0.31
ACE P12821 1/20 0.31
CPA1 P15085 1/20 0.31
ACE2 Q9BYF1 1/20 0.31
TSHR P16473 2/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL355795 1.00 LDHA (0.38) LDHASRRFFAR3CYP2C9HDAC3
SCHEMBL30532234 0.88 TSHR (0.33) TSHR
SCHEMBL10777977 0.81 HDAC1 (0.41) LDHASRRFFAR3HDAC3HDAC1
SCHEMBL29411100 0.78 GAA (0.41) LMNAEGLN1
SCHEMBL10780876 0.78 CA2 (0.42) ACE2TSHR
SCHEMBL29199347 0.77 LDHA (0.40) LDHASRRCYP2C9TSHRLMNA
SCHEMBL10031543 0.76
SCHEMBL16445585 0.74 GPR84 (0.48) ACE2TSHR
SCHEMBL2021291 0.74 USP2 (0.44) LDHASRRFFAR3HDAC3HDAC1
SCHEMBL3838841 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105133-A1 TNF- Α AND IL-17 INHIBITOR COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES DAMLE LATHA (IN) 2026-05-21 WO claimed
US-10724008-B2 Ketoreductases C-LECTA GMBH (DE) 2020-07-28 US claimed
WO-2020026143-A1 PROCESS FOR MAKING A CONSUMER PRODUCT COMPRISING MODIFIED POLYSACCHARIDES PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) 2020-02-06 WO claimed
US-20200040108-A1 PROCESS FOR MAKING A CONSUMER PRODUCT COMPRISING MODIFIED POLYSACCHARIDES PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA 2020-02-06 US claimed
EP-3604346-A1 PROCESS FOR MAKING A CONSUMER PRODUCT COMPRISING MODIFIED POLYSACCHARIDES Procter & Gamble International Operations SA (CH) 2020-02-05 EP claimed
US-10093905-B2 Ketoreductases C-LECTA GMBH (DE) 2018-10-09 US claimed
EP-3134519-B1 KETOREDUCTASES C LECTA GMBH (DE) 2018-06-06 EP claimed
US-20170218345-A1 KETOREDUCTASES C-LECTA GMBH (DE) 2017-08-03 US claimed
EP-3134519-A1 KETOREDUCTASES c-LEcta GmbH (DE) 2017-03-01 EP claimed
EP-2569275-B1 A PROCESS FOR THE HYDROGENATION OF KETOESTERS LONZA AG (CH) 2016-01-27 EP claimed
US-20070243594-A1 Oxidoreductase from Pichia Capsulata IEP GMBH (DE) 2007-10-18 US claimed
US-20070173660-A1 Catalytic composition and process for asymmetric hydrogenation PHOENIX CHEMICALS LIMITED (GB) 2007-07-26 US claimed
CN-1839153-A Oxidoreductase from pichia capsulata IEP GMBH (DE) 2006-09-27 CN claimed
WO-2006091470-A2 IMPROVED HALOHYDRIN DEHALOGENASES AND RELATED POLYNUCLEOTIDES CODEXIS, INC. (US) 2006-08-31 WO claimed
US-7056540-B2 Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root Daucus carota COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-06-06 US claimed
US-20060099700-A1 Enzymatic polypeptide comprising halogenase activity for use in production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters; bioremediation; pollution control INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2006-05-11 US claimed
EP-1628762-A1 CATALYTIC COMPOSITION AND PROCESS FOR ASYMMETRIC HYDROGENATION Phoenix Chemicals Limited (GB) 2006-03-01 EP claimed
WO-2004103560-A1 CATALYTIC COMPOSITION AND PROCESS FOR ASYMMETRIC HYDROGENATION PHOENIX CHEMICALS LIMITED (GB) 2004-12-02 WO claimed
US-20040082043-A1 Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root daucus carota COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-04-29 US claimed
US-6218157-B1 EFFICIENT METHOD BY REACTING A 4-HALOACETOACETIC ACID ESTER WITH PURIFIED ENZYME TO FORM (S)-4-HALO-3-HYDROXYBUTYRIC ACID ESTER DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173660-A1 Catalytic composition and process for asymmetric hydrogenation KHK, HK2, HK1 LDHA 153/4885SRR 584/4885FFAR3 3131/4885
US-20060099700-A1 Enzymatic polypeptide comprising halogenase activity for use in production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters; bioremediation; pollution control HDHD5, HPD, CPB1 LDHA 418/4885SRR 1208/4885FFAR3 1136/4885
US-20200040108-A1 PROCESS FOR MAKING A CONSUMER PRODUCT COMPRISING MODIFIED POLYSACCHARIDES MGAM, FUT5, FUT6 LDHA 1504/4885SRR 278/4885FFAR3 2040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.