Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577852 | 0.84 | AURKB (0.61) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL3575391 | 0.83 | DHODH (0.47) | MEN1KMT2APRKD3MAP4K4PIM1 | |
| SCHEMBL6810427 | 0.83 | PKN1 (0.58) | PRKD3MAP4K4PIM1CLK2CAMK2D | |
| SCHEMBL3585597 | 0.83 | DHODH (0.45) | MEN1KMT2ADHODHCYP2D6GRK6 | |
| SCHEMBL6948237 | 0.81 | TSHR (0.50) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3575168 | 0.79 | SIRT2 (0.52) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3580405 | 0.76 | MMP2 (0.50) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3580810 | 0.74 | CHEK1 (0.59) | MAP4K4PIM1CLK2MAP4K2DYRK1A | |
| SCHEMBL6583754 | 0.74 | KDM4E (0.47) | KDM4EMEN1MITFALDH1A1MAPT | |
| SCHEMBL5800533 | 0.72 | HTT (0.71) | KDM4EMEN1MITFALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781596-B1 | Substituted 2-phenylbenzimidazoles, the production thereof and their use | ABBOTT LABORATORIES (US) | 2010-08-24 | — | — | US | disclosed |