Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50300 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TSHRSLC5A2SLC5A1TDP1 | |
| SCHEMBL7793896 | 0.72 | IDO1 (0.41) | ALDH1A1TDP1LMNA | |
| SCHEMBL23522757 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRSLC5A2SLC5A1HDAC8 | |
| SCHEMBL32670784 | 0.72 | ALDH1A1 (0.55) | ALDH1A1TSHRSLC5A2SLC5A1TDP1 | |
| SCHEMBL110859 | 0.72 | CALM1 (0.52) | ALDH1A1TSHRLMNA | |
| SCHEMBL1562120 | 0.70 | ALDH1A1 (0.59) | ALDH1A1TSHRSLC5A2SLC5A1PSMD14 | |
| SCHEMBL1882237 | 0.70 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL28169834 | 0.69 | ALDH1A1 (0.92) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL18545502 | 0.68 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL28858334 | 0.68 | ALDH1A1 (0.50) | ALDH1A1TSHRSLC5A2SLC5A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140058008-A1 | Ocular Lens | INNOLENE LLC (US) | 2014-02-27 | — | — | US | disclosed |
| US-8585940-B2 | Ocular lens | INNOLENE LLC (US) | 2013-11-19 | — | — | US | disclosed |
| US-20100283164-A1 | Ocular Lens | EYEDEAL HONGKONG LIMITED (HK) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140058008-A1 | Ocular Lens | CRYAA, CRYZ, CRYAB | ALDH1A1 3265/4885TSHR 3522/4885SLC5A2 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.