Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766426 | 0.85 | KDM4E (0.36) | KDM4EMAPT | |
| SCHEMBL5768181 | 0.85 | KDM4E (0.33) | KDM4EMAPT | |
| SCHEMBL5764009 | 0.84 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL5766878 | 0.82 | CCNE2 (0.42) | KDM4EMAPT | |
| SCHEMBL5766255 | 0.82 | TAS1R3 (0.34) | KDM4E | |
| SCHEMBL5765490 | 0.81 | KDM4E (0.37) | KDM4EMAPT | |
| SCHEMBL3951080 | 0.81 | PDK1 (0.45) | — | |
| SCHEMBL4688651 | 0.81 | PDK1 (0.45) | — | |
| SCHEMBL5763655 | 0.81 | PDK1 (0.45) | — | |
| SCHEMBL5764200 | 0.81 | ALDH1A1 (0.40) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267796-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-2077122-A1 | THERAPEUTIC AGENTS FOR IRRITABLE BOWEL SYNDROME | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267796-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | SLC10A2, ADORA3, HRH2 | KDM4E 3186/4885MAPT 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.