Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428976 | 0.91 | CALM1 (0.47) | TSHRMAPK1CALM1CAMKK2BCHE | |
| SCHEMBL1136011 | 0.90 | CARM1 (0.46) | TSHRMAPK1CARM1PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL919008 | 0.88 | CARM1 (0.45) | TSHRMAPK1CARM1PRMT6PRMT8 | |
| Acetic Acid SCHEMBL1178577 | 0.84 | CARM1 (0.41) | CARM1PRMT6PRMT8BCHEHCRTR2 | |
| Glycolic Acid SCHEMBL28669797 | 0.82 | ACKR3 (0.39) | CARM1PRMT6PRMT8BCHEHCRTR2 | |
| Hydrochloric Acid SCHEMBL9469779 | 0.81 | KCNH2 (0.49) | TSHRMAPK1BCHEOPRM1DRD3 | |
| SCHEMBL18419395 | 0.80 | SIGMAR1 (0.56) | TSHRCARM1PRMT6PRMT8MAOA | |
| SCHEMBL1155814 | 0.77 | ALDH1A1 (0.40) | CALM1CAMKK2BCHEALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL7642810 | 0.77 | CARM1 (0.38) | CARM1PRMT6PRMT8CALM1CAMKK2 | |
| Hydrochloric Acid SCHEMBL28360924 | 0.76 | CARM1 (0.39) | TSHRCARM1PRMT6PRMT8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066610-A1 | Sealant System and Methods of Use and Manufacture | TMSCSP LLC (US) | 2025-02-27 | — | — | US | claimed |
| WO-2023114489-A9 | MOISTURE-RESISTANT COMPOSITIONS FOR ROOF COATINGS | HENRY COMPANY, LLC (US) | 2024-10-10 | — | — | WO | claimed |
| US-20230399522-A1 | Self-Cleaning, Dirt Pick-Up Resistant Compositions for Roof Coatings | HENRY COMPANY, LLC | 2023-12-14 | — | — | US | claimed |
| WO-2023114489-A1 | MOISTURE-RESISTANT COMPOSITIONS FOR ROOF COATINGS | HENRY COMPANY, LLC (US) | 2023-06-22 | — | — | WO | claimed |
| US-11680171-B2 | Self-cleaning, dirt pick-up resistant compositions for roof coatings | HENRY COMPANY, LLC (US) | 2023-06-20 | — | — | US | claimed |
| US-20200392337-A1 | Sealant System and Methods of Use and Manufacture | TMSCSP LLC (US) | 2020-12-17 | — | — | US | claimed |
| US-20200339759-A1 | Self-Cleaning, Dirt Pick-Up Resistant Compositions for Roof Coatings | HENRY COMPANY, LLC | 2020-10-29 | — | — | US | claimed |
| WO-2020113005-A1 | SELF-CLEANING, DIRT PICK-UP RESISTANT COMPOSITIONS FOR ROOF COATINGS | HENRY COMPANY, LLC (US) | 2020-06-04 | — | — | WO | claimed |
| US-9896601-B2 | Dirt pick-up resistant silicone compositions | Gaco Western, LLC (US) | 2018-02-20 | — | — | US | claimed |
| US-20160347956-A1 | DIRT PICK-UP RESISTANT SILICONE COMPOSITIONS | AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) | 2016-12-01 | — | — | US | claimed |
| US-8703866-B2 | Room temperature curable organopolysiloxane composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-04-22 | — | — | US | claimed |
| EP-2474573-B1 | Room temperature vulcanizable organopolysiloxane composition, its production method, and article coated by cured organopolysiloxane composition | SHINETSU CHEMICAL CO (JP) | 2014-03-19 | — | — | EP | claimed |
| EP-2474573-A1 | Room temperature vulcanizable organopolysiloxane composition, its production method, and article coated by cured organopolysiloxane composition | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-07-11 | — | — | EP | claimed |
| US-12601178-B2 | Bonding adhesive and adhered roofing systems prepared using the same | AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) | 2026-04-14 | — | — | US | disclosed |
| US-12595397-B2 | Surface-modified silicone roofing materials and related systems and related methods | BMIC LLC (US) | 2026-04-07 | — | — | US | disclosed |
| US-12565566-B2 | Room-temperature-curable organopolysiloxane composition and production method for same | SHIN-ETSU SILICONE KOREA CO., LTD. (KR) | 2026-03-03 | — | — | US | disclosed |
| US-20100130658-A1 | ROOM TEMPERATURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-2130873-A1 | Room temperature curable organopolysiloxane composition | Shin-Etsu Chemical Co., Ltd. (JP) | 2009-12-09 | — | — | EP | disclosed |
| US-20090286916-A1 | ROOM TEMPERATURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20070276085-A1 | Containing a triorganosilanol (trimethylsilanol), organosilane containing at least 3 hydrolyzable groups ((3-aminopropyl)triethoxysilane), and calcium carbonate; excellent adhesion to a variety of substrates, especially aluminum and rocks | SHIN-ETSU CHEMICAL CO., LTD. | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12565566-B2 | Room-temperature-curable organopolysiloxane composition and production method for same | COL1A1, COL2A1, REV1 | TSHR 965/4885MAPK1 4034/4885CARM1 733/4885 |
| US-12595397-B2 | Surface-modified silicone roofing materials and related systems and related methods | L1CAM, MSR1, STRA6 | TSHR 274/4885MAPK1 2391/4885CARM1 731/4885 |
| US-12601178-B2 | Bonding adhesive and adhered roofing systems prepared using the same | ITGAM, EPCAM, ADRM1 | TSHR 4224/4885MAPK1 3666/4885CARM1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.