Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245654 | 0.89 | SMN1; SMN2 (0.42) | NR1H2CYP4F2CYP4A11SMN1; SMN2USP2 | |
| SCHEMBL18728345 | 0.89 | CYP4F2 (0.46) | NR1H2CYP4F2CYP4A11SMN1; SMN2USP2 | |
| SCHEMBL3634028 | 0.87 | L3MBTL1 (0.40) | NR1H2CYP4F2CYP4A11SMN1; SMN2USP2 | |
| SCHEMBL22233140 | 0.87 | ADORA1 (0.39) | NR1H2CYP4F2CYP4A11SMN1; SMN2USP2 | |
| SCHEMBL3634007 | 0.87 | SMN1; SMN2 (0.37) | NR1H2CYP4F2CYP4A11SMN1; SMN2USP2 | |
| SCHEMBL21749176 | 0.86 | L3MBTL1 (0.46) | CYP4F2CYP4A11L3MBTL1MEN1KMT2A | |
| SCHEMBL7309006 | 0.85 | USP2 (0.43) | NR1H2CYP4F2CYP4A11SMN1; SMN2USP2 | |
| SCHEMBL23390562 | 0.84 | NR1H2 (0.42) | NR1H2CYP4F2CYP4A11SMN1; SMN2USP2 | |
| SCHEMBL426525 | 0.83 | SMN1; SMN2 (0.41) | NR1H2SMN1; SMN2USP2ADORA1MEN1 | |
| SCHEMBL22233978 | 0.82 | ALDH1A1 (0.34) | NR1H2CYP4F2CYP4A11SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503452-B2 | Antimicrobial compounds and methods | CURZA GLOBAL, LLC (US) | 2025-12-23 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230026696-A1 | TRPV4 RECEPTOR LIGANDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-01-26 | — | — | US | disclosed |
| US-20230026696-A1 | TRPV4 RECEPTOR LIGANDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-01-26 | — | — | US | disclosed |
| EP-4061124-A1 | TRPV4 RECEPTOR LIGANDS | University of Utah Research Foundation (US) | 2022-09-28 | — | — | EP | disclosed |
| CN-115052478-A | TRPV4 receptor ligands | 犹他大学研究基金会 | 2022-09-13 | — | — | CN | disclosed |
| EP-3911644-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | Curza Global LLC (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2021102314-A1 | TRPV4 RECEPTOR LIGANDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-05-27 | — | — | WO | disclosed |
| WO-2021102314-A1 | TRPV4 RECEPTOR LIGANDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-05-27 | — | — | WO | disclosed |
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |
| EP-2155666-A1 | AZETIDINE DERIVATIVES AND THEIR USE AS PROSTAGLANDIN E2 ANTAGONISTS | Pfizer Limited (GB) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008139287-A1 | AZETIDINE DERIVATIVES AND THEIR USE AS PROSTAGLANDIN E2 ANTAGONISTS | PFIZER LIMITED (GB) | 2008-11-20 | — | — | WO | disclosed |
| US-20080280877-A1 | Azetidines | PFIZER INC | 2008-11-13 | — | — | US | disclosed |
| US-20080280877-A1 | Azetidines | PFIZER INC | 2008-11-13 | — | — | US | disclosed |
| US-20080280877-A1 | Azetidines | PFIZER INC | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | NR1H2 4027/4885CYP4F2 4672/4885CYP4A11 4608/4885 |
| US-20230026696-A1 | TRPV4 RECEPTOR LIGANDS | TRPV4, TRPV2, TRPV3 | NR1H2 231/4885CYP4F2 2169/4885CYP4A11 1142/4885 |
| US-20080280877-A1 | Azetidines | PTGER2, PTGER1, PTGDR2 | NR1H2 180/4885CYP4F2 1549/4885CYP4A11 771/4885 |
| US-12503452-B2 | Antimicrobial compounds and methods | MPO, NISCH, RPN2 | NR1H2 4027/4885CYP4F2 4672/4885CYP4A11 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.