SCHEMBL363661

SCHEMBL363661

O=C(O)Oc1coc(Br)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6653841 0.77 NPC1 (0.38) NPC1POLB
SCHEMBL322525 0.70 LMNA (0.40)
SCHEMBL363660 0.68
SCHEMBL10523416 0.68 GAA (0.41) NPC1POLB
SCHEMBL2480841 0.68 CHRNB2 (0.32)
SCHEMBL3504737 0.65 LDHA (0.54)
SCHEMBL465132 0.65 LMNA (0.52) POLB
SCHEMBL7258244 0.64 KDM4E (0.36)
SCHEMBL1001721 0.64 RXRA (0.42)
SCHEMBL9828429 0.63 CA2 (0.41) NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593447-B1 3-PYRIDYL-HETEROARYLCARBOXAMIDE COMPOUNDS AS PESTICIDES BAYER IP GMBH (DE) 2016-08-17 EP disclosed
EP-2593447-A2 NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer Intellectual Property GmbH (DE) 2013-05-22 EP disclosed
WO-2012007500-A2 NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2012-01-19 WO disclosed