Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.34 |
| ▸ | F9 | P00740 | 4/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363071 | 0.92 | BRD4 (0.37) | BRD4GPBAR1F9MCL1PPARG | |
| SCHEMBL364524 | 0.91 | PTGS2 (0.36) | BRD4GPBAR1F9CTSA | |
| SCHEMBL361665 | 0.88 | HPGD (0.37) | BRD4GPBAR1 | |
| SCHEMBL362599 | 0.86 | BRD4 (0.40) | BRD4GPBAR1 | |
| SCHEMBL362147 | 0.86 | MET (0.34) | BRD4GPBAR1F9NTRK1 | |
| SCHEMBL363606 | 0.86 | GPBAR1 (0.35) | BRD4GPBAR1 | |
| SCHEMBL364618 | 0.85 | MET (0.42) | BRD4GPBAR1NTRK1 | |
| SCHEMBL361844 | 0.84 | GPBAR1 (0.44) | BRD4GPBAR1F9CTSAS1PR1 | |
| SCHEMBL364504 | 0.83 | GPBAR1 (0.40) | BRD4GPBAR1F9CTSAKMT2A | |
| SCHEMBL369846 | 0.82 | BRD4 (0.40) | BRD4GPBAR1F9CTSAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | claimed |
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |