SCHEMBL3655402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4592142	0.98	TDP1 (0.53)	TDP1RAB9ABCHEL3MBTL1ALDH1A1
	SCHEMBL811440	0.94	TDP1 (0.61)	TDP1RAB9ABCHEL3MBTL1ALDH1A1
	SCHEMBL810857	0.92	TDP1 (0.59)	TDP1RAB9ABCHEL3MBTL1ALDH1A1
	SCHEMBL1104296	0.89	TDP1 (0.63)	TDP1RAB9ACYP4F2CYP4A11SLC7A5
	SCHEMBL21143362	0.87	TDP1 (0.61)	TDP1RAB9AALDH1A1CYP4F2CYP4A11
	SCHEMBL3877623	0.87	TDP1 (0.61)	TDP1RAB9AALDH1A1CYP4F2CYP4A11
	SCHEMBL810821	0.87	L3MBTL1 (0.57)	TDP1RAB9ABCHEL3MBTL1ALDH1A1
	SCHEMBL6057136	0.86	LMNA (0.56)	TDP1RAB9AALDH1A1ESR1
	SCHEMBL28807886	0.85	LMNA (0.58)	TDP1RAB9AALDH1A1ESR1
	SCHEMBL28437780	0.85	LMNA (0.58)	TDP1RAB9AALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.