Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367564 | 0.89 | HPGD (0.50) | — | |
| SCHEMBL365591 | 0.88 | HPGD (0.49) | — | |
| SCHEMBL366310 | 0.86 | ALDH1A1 (0.52) | — | |
| SCHEMBL365543 | 0.81 | REN (0.53) | REN | |
| SCHEMBL365014 | 0.79 | KDM4E (0.48) | — | |
| SCHEMBL364594 | 0.78 | EGFR (0.44) | — | |
| SCHEMBL365565 | 0.78 | KMT2A (0.52) | — | |
| SCHEMBL364207 | 0.76 | EGFR (0.47) | — | |
| SCHEMBL12918548 | 0.74 | KDM4E (0.50) | REN | |
| SCHEMBL364969 | 0.74 | KDM4E (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |